{"id":"W4404246252","doi":"10.1161/circ.150.suppl_1.4139196","title":"Abstract 4139196: Long-term effectiveness and safety of mavacamten in a real-world, multi-center, global study: Preliminary results of COLLIGO-HCM from a diverse cohort in the United States","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Center (category theory); Cohort; Term (time); Medical emergency; Gerontology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005478461,0.0001061077,0.0001621177,0.00006637234,0.00001956642,0.00001132971,0.00009409106,0.00007937275,0.00000359936],"category_scores_gemma":[0.00006000355,0.00008137284,0.00003780574,0.0002776701,0.00003961864,0.000007405994,0.00006727428,0.00007313162,5.583914e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004878049,"about_ca_system_score_gemma":0.00002317002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001505871,"about_ca_topic_score_gemma":0.0007046505,"domain_scores_codex":[0.9989896,0.0002573999,0.0002555182,0.000272964,0.0001146749,0.0001098619],"domain_scores_gemma":[0.9996066,0.0001363836,0.00006471938,0.000129225,0.00003638754,0.0000266945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002217387,0.0007470249,0.8699731,0.0001228315,0.00008987645,0.00003759375,0.0003278335,0.002246846,0.1220444,0.00001199976,0.00001076941,0.002170324],"study_design_scores_gemma":[0.002925936,0.0002550086,0.9883285,0.0001496656,0.00003187435,0.000001124836,0.0001119221,0.002357802,0.005705749,0.00004231932,0.00001193289,0.00007823153],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983757,0.0002154549,0.000186369,0.00001203892,0.00008344241,0.0008868198,0.0002073525,0.000006315664,0.00002648807],"genre_scores_gemma":[0.9990065,0.0002962111,0.00001971074,0.00001214464,0.00001806899,0.00003414324,0.0006062731,0.000005775308,0.000001176553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1183553,"threshold_uncertainty_score":0.3318288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02429918311950756,"score_gpt":0.3262655127498378,"score_spread":0.3019663296303303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}