{"id":"W4404246252","doi":"10.1161/circ.150.suppl_1.4139196","title":"Abstract 4139196: Long-term effectiveness and safety of mavacamten in a real-world, multi-center, global study: Preliminary results of COLLIGO-HCM from a diverse cohort in the United States","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Center (category theory); Cohort; Term (time); Medical emergency; Gerontology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003463501,0.0003633536,0.0005360965,0.0004180717,0.0003985697,0.0008093034,0.0003563129,0.000407989,0.001659883],"category_scores_gemma":[0.003205081,0.0001618995,0.0007910897,0.0006664625,0.0004090928,0.0005794275,0.0005494051,0.0005037841,0.000340134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003535857,"about_ca_system_score_gemma":0.0005268269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001149802,"about_ca_topic_score_gemma":0.002387958,"domain_scores_codex":[0.9984819,0.0007871033,0.0001663902,0.0002231632,0.0002448754,0.00009656431],"domain_scores_gemma":[0.9958061,0.0009463305,0.002046232,0.0004298016,0.0003816095,0.0003898959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02277854,0.001784963,0.9451625,0.0004267953,0.002359268,0.0001733159,0.0005195781,0.0002114159,0.002091404,0.00003991085,0.001390498,0.02306191],"study_design_scores_gemma":[0.002095709,0.01100658,0.9833909,0.00006518712,0.0008907627,0.0002786408,0.000227865,0.0002005987,0.0004379183,0.00002440464,0.0013616,0.00001971006],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963573,0.001258256,0.0001368805,0.00009137874,0.00001011494,0.0001376832,0.00151455,0.000009865544,0.000483989],"genre_scores_gemma":[0.9962257,0.0004556186,0.000270796,0.0002168712,0.00004693972,0.0001310171,0.002473581,0.000007028234,0.000172459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003463501,"threshold_uncertainty_score":0.01831698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02429918311950756,"score_gpt":0.3262655127498378,"score_spread":0.3019663296303303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}