{"id":"W4404256900","doi":"10.1093/neuonc/noae165.0279","title":"CSIG-30. EXPLORING THE ROLE OF CAPICUA (CIC) IN RESISTANCE MECHANISMS OF MEK INHIBITORS IN GLIOBLASTOMA","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Glioblastoma; Resistance (ecology); Cancer research; Chemistry; Medicine; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001930526,0.0003383618,0.0004822175,0.000412327,0.0001810637,0.000296225,0.0003800805,0.0003627458,0.002615945],"category_scores_gemma":[0.00009413045,0.0001461785,0.0003384144,0.0003308437,0.00017251,0.0001683257,0.0002149209,0.000620197,0.0007869449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005904982,"about_ca_system_score_gemma":0.000638038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00142141,"about_ca_topic_score_gemma":0.002391505,"domain_scores_codex":[0.9999024,0.00001025465,0.000005124542,0.00001223486,0.00003136427,0.00003870597],"domain_scores_gemma":[0.999943,0.000003383921,0.00000844951,0.000005381988,0.000009374473,0.00003038462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002631917,0.0008358672,0.00373651,0.001099796,0.0001134197,0.0007498005,0.00005522559,0.001192811,0.9000415,0.001244633,0.005104869,0.08319367],"study_design_scores_gemma":[0.00148545,0.01670349,0.07742987,0.0001693998,0.0004555367,0.003973342,0.000155895,0.00833425,0.795069,0.00103562,0.0951139,0.00007419145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9547724,0.02411004,0.001748639,0.0009687585,0.0002331138,0.0003729149,0.001992098,0.0003171778,0.01548487],"genre_scores_gemma":[0.9851291,0.006231731,0.001237709,0.0004499038,0.00004278615,0.0001294693,0.002593272,0.00002284837,0.004163074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002615945,"threshold_uncertainty_score":0.008751273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01968387628317661,"score_gpt":0.2775548213384806,"score_spread":0.257870945055304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}