{"id":"W4404293285","doi":"10.1007/s13555-024-01303-z","title":"Rocatinlimab Improves Patient-Reported Outcomes in Adults with Moderate-to-Severe Atopic Dermatitis: Results from a Double-Blind Placebo-Controlled Phase 2b Study","year":2024,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"Kyowa Kirin International","keywords":"Atopic dermatitis; Placebo; Double blind; Medicine; Dermatology; Double blind study; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003265732,0.001036088,0.002169916,0.0002936549,0.0002866272,0.0007076798,0.0005451405,0.001044802,0.002667096],"category_scores_gemma":[0.002311875,0.0003849356,0.001275796,0.0002809343,0.0005007648,0.0005407597,0.0002441623,0.001215141,0.0004022545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002884458,"about_ca_system_score_gemma":0.0005958493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002959814,"about_ca_topic_score_gemma":0.0006301023,"domain_scores_codex":[0.9989177,0.0006385495,0.0001014287,0.0001393306,0.000111222,0.00009170481],"domain_scores_gemma":[0.998741,0.0004410355,0.0003741183,0.00009047135,0.0001189737,0.0002344995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8603135,0.02658422,0.008926111,0.001988658,0.003263008,0.0001109573,0.0001852768,0.0004246606,0.01503063,0.00004730079,0.001474181,0.08165154],"study_design_scores_gemma":[0.6475412,0.2902943,0.05762989,0.00008578247,0.00147808,0.0001758427,0.00004162598,0.000500883,0.001303759,0.00005559378,0.0008639841,0.00002902389],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917819,0.005480815,0.0003527823,0.0002004651,0.00008640663,0.0009913648,0.0004431664,0.00006082225,0.0006022122],"genre_scores_gemma":[0.9946018,0.001919244,0.0007697903,0.0004913883,0.0002123066,0.0009181379,0.0005881285,0.00001343415,0.0004856843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003265732,"threshold_uncertainty_score":0.0172711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786456798619309,"score_gpt":0.3013805032968833,"score_spread":0.2835159353106902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}