{"id":"W4404304760","doi":"10.5267/j.ccl.2024.7.002","title":"Base and additive free click chemistry strategy to accomplish the synthesis of amalgamated pyrazolo-triazole heterocyclic scaffolds and their molecular docking study","year":2024,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of the Punjab","keywords":"Chemistry; Click chemistry; Triazole; Docking (animal); Combinatorial chemistry; Stereochemistry; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001768217,0.0005336629,0.0004649066,0.00002899123,0.0002143793,0.0002627315,0.0007268049,0.0001576755,0.0003522788],"category_scores_gemma":[0.0001703809,0.0004417465,0.000169785,0.0003284153,0.0003190824,0.000109258,0.000515839,0.0004484594,0.000004905426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008414645,"about_ca_system_score_gemma":0.00004009038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001734077,"about_ca_topic_score_gemma":0.000001157671,"domain_scores_codex":[0.9976779,0.00002388416,0.0005818859,0.0009591563,0.0002940538,0.0004631544],"domain_scores_gemma":[0.9978898,0.0005443674,0.0001763083,0.001055344,0.00006840996,0.0002657631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003173869,0.0002044498,0.0003281634,0.00112092,0.0002076426,0.00001845356,0.000454733,0.00004890762,0.9858752,0.000005497593,0.000840492,0.01086375],"study_design_scores_gemma":[0.0004390109,0.000004037332,0.0001514634,0.0005310669,0.0001693276,0.00004773114,0.001598925,0.0006536303,0.9948997,0.00006170974,0.0009921012,0.0004512971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954791,0.001331996,0.00003851831,0.001198925,0.0000431782,0.0002687392,0.0006581869,0.0001933064,0.0007880203],"genre_scores_gemma":[0.9989927,0.0000880544,0.00001473771,0.00005160343,0.0002703216,0.000388938,0.0001139629,0.00005984148,0.00001987232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01041245,"threshold_uncertainty_score":0.9998034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01648520978673581,"score_gpt":0.2647679386303876,"score_spread":0.2482827288436518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}