{"id":"W4404305779","doi":"10.1158/1557-3265.liqbiop24-b021","title":"Abstract B021: tRNA fragments extracted from patient plasma extra cellular vesicles display potential as biomarkers for high-grade glioma","year":2024,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Atlantic Cancer Research Institute; Dalhousie University","funders":"","keywords":"Glioma; Vesicle; Cancer research; Chemistry; Medicine; Pathology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002165509,0.0002586769,0.0003443717,0.0007812313,0.000193391,0.0005512389,0.0001741963,0.0004911707,0.003449915],"category_scores_gemma":[0.0004768514,0.00009016932,0.0002358642,0.0004308451,0.0001288949,0.0001718487,0.0002669063,0.0003507892,0.0008579841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002007376,"about_ca_system_score_gemma":0.0001208771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000541114,"about_ca_topic_score_gemma":0.00037564,"domain_scores_codex":[0.9998769,0.00001686402,0.00001380596,0.00003136503,0.00003938411,0.00002172642],"domain_scores_gemma":[0.9998807,0.00003821169,0.00003023309,0.000007973465,0.00002845759,0.00001438566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001113668,0.00004172257,0.01616849,0.0002191937,0.00005554672,0.0004459707,0.00006668703,0.0001713311,0.9654651,0.0001083703,0.0006240341,0.01551983],"study_design_scores_gemma":[0.00005639855,0.000672253,0.3423383,0.00005193745,0.0001971276,0.006361993,0.000382936,0.002944228,0.6406294,0.0005671951,0.005758973,0.00003935883],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990499,0.001830674,0.003615031,0.0001867437,0.00006400132,0.00002787408,0.002421304,0.0001617856,0.001193647],"genre_scores_gemma":[0.9908303,0.0005932605,0.003416285,0.0001105079,0.00002390208,0.00002388948,0.002922849,0.00004680823,0.002032214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003449915,"threshold_uncertainty_score":0.01154113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0830709705604627,"score_gpt":0.4306140020026961,"score_spread":0.3475430314422334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}