{"id":"W4404320114","doi":"10.5267/j.ccl.2024.9.004","title":"Synthesis and some chemical transformations of novel 1-oxo-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-8-carboxylic acids and their benzoannelated analogues","year":2024,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and Reactivity of Heterocycles","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Enamine","keywords":"Chemistry; Carboxylic acid; Chemical synthesis; Chemical shift; Combinatorial chemistry; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001301572,0.0003808242,0.0002727903,0.0001652924,0.0001378189,0.0001463341,0.0002491819,0.0002628067,0.0009027343],"category_scores_gemma":[0.0001277354,0.000152312,0.0002893661,0.0001604675,0.0001559303,0.0002559405,0.0001935207,0.0003908722,0.0004469655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001464092,"about_ca_system_score_gemma":0.0002704253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002727763,"about_ca_topic_score_gemma":0.0005084937,"domain_scores_codex":[0.9998977,0.00001629336,0.000009971032,0.00002271677,0.00002271673,0.00003051179],"domain_scores_gemma":[0.9999417,0.000003940685,0.00001887221,0.000005137015,0.00001280162,0.00001763548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006977297,0.00002785745,0.00007812212,0.0001656052,0.000008867533,0.0001314566,0.00003153954,0.0002618589,0.9951301,0.0002681102,0.00003621079,0.003790514],"study_design_scores_gemma":[0.00004201708,0.0008827415,0.001270895,0.000008776487,0.0000231626,0.0003726764,0.00002668355,0.0003346275,0.988316,0.00008575212,0.00862024,0.00001635054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9501276,0.01650557,0.02606917,0.0002369851,0.0001697163,0.0002380122,0.0008194095,0.0001232318,0.005710469],"genre_scores_gemma":[0.9687264,0.007101276,0.0181854,0.00007615172,0.00004706395,0.0001478643,0.000669054,0.00001979994,0.005026937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009027343,"threshold_uncertainty_score":0.003019989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617719433152446,"score_gpt":0.230255818121198,"score_spread":0.2140786237896736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}