{"id":"W4404320114","doi":"10.5267/j.ccl.2024.9.004","title":"Synthesis and some chemical transformations of novel 1-oxo-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-8-carboxylic acids and their benzoannelated analogues","year":2024,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and Reactivity of Heterocycles","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Enamine","keywords":"Chemistry; Carboxylic acid; Chemical synthesis; Chemical shift; Combinatorial chemistry; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001226656,0.0004066879,0.000483519,0.000081082,0.00009565288,0.0001015088,0.0002254994,0.0002198625,0.0001538383],"category_scores_gemma":[0.00007093748,0.0003425013,0.0002153624,0.0001256097,0.0004085602,0.0003033945,0.00007895113,0.0004377273,0.00000306971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005468311,"about_ca_system_score_gemma":0.00003027254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008540208,"about_ca_topic_score_gemma":3.579026e-7,"domain_scores_codex":[0.9984086,0.0000112127,0.0004519304,0.0005350445,0.0002176353,0.0003755513],"domain_scores_gemma":[0.9989936,0.000391414,0.0001052432,0.0003075026,0.00002508607,0.0001771632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001769576,0.0001447056,0.00013437,0.001799582,0.0002068067,0.00000333991,0.000465667,0.000006047022,0.9792491,0.000009809277,0.0001534336,0.01780941],"study_design_scores_gemma":[0.0003301202,0.000001730201,0.000107711,0.0008198818,0.0001457069,0.00007192874,0.0001787545,0.003679509,0.9930814,0.00004501927,0.001156934,0.0003813153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910159,0.006228087,0.0001212124,0.001652467,0.0000963493,0.00006829213,0.0003152764,0.0001736134,0.0003288613],"genre_scores_gemma":[0.9986349,0.0008613255,0.00005949611,0.00002616025,0.0002375504,0.00004072483,0.00009211178,0.00004255753,0.000005225672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01742809,"threshold_uncertainty_score":0.9999027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617719433152446,"score_gpt":0.230255818121198,"score_spread":0.2140786237896736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}