{"id":"W4404323584","doi":"10.1161/circ.150.suppl_1.4132223","title":"Abstract 4132223: Mavacamten in adolescent patients with symptomatic obstructive hypertrophic cardiomyopathy: design of the Phase 3 SCOUT-HCM trial","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Hypertrophic cardiomyopathy; Cardiology; Internal medicine; Cardiomyopathy; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002300176,0.00121401,0.001543613,0.0002383928,0.0004184958,0.0009150883,0.0006402169,0.001647393,0.006073583],"category_scores_gemma":[0.001388103,0.0004224432,0.001244328,0.0002339027,0.0006191104,0.0006571584,0.0003264448,0.002288204,0.0009371249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004617016,"about_ca_system_score_gemma":0.001457581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005594133,"about_ca_topic_score_gemma":0.001829496,"domain_scores_codex":[0.9994971,0.0003124329,0.00002546692,0.0000565762,0.00003337146,0.00007507491],"domain_scores_gemma":[0.999239,0.00015778,0.000165226,0.00005596889,0.00007505252,0.0003070185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9223077,0.02497999,0.005674187,0.001261794,0.001290861,0.0002145683,0.0001853344,0.0008385513,0.00858101,0.0005014429,0.005748031,0.02841661],"study_design_scores_gemma":[0.8777159,0.1126954,0.005210021,0.00008609953,0.0004651572,0.00009204735,0.00003937881,0.0005929618,0.0005615077,0.0002773899,0.002247634,0.00001644448],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9703454,0.00375349,0.0007709336,0.001339862,0.0003894512,0.01690046,0.002227433,0.0001183825,0.004154544],"genre_scores_gemma":[0.9593323,0.002534762,0.003817623,0.002922293,0.0006579568,0.02495884,0.002326655,0.00003906866,0.0034105],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.006073583,"threshold_uncertainty_score":0.02031821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02850384535288984,"score_gpt":0.2723155684146921,"score_spread":0.2438117230618023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}