{"id":"W4404326054","doi":"10.1002/alz.14361","title":"Integrated cerebellar radiomic‐network model for predicting mild cognitive impairment in Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; H. Lundbeck A/S; Servier; Natural Science Foundation of Liaoning Province; National Natural Science Foundation of China; Eisai; Takeda Pharmaceutical Company; IXICO; Fudan University; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Roche; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Drug Discovery Foundation; GE Healthcare; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; AbbVie; Alzheimer's Association","keywords":"Cognitive impairment; Disease; Cognition; Neuroscience; Psychology; Medicine; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001056483,0.00118628,0.0008046052,0.001500671,0.0002908818,0.0007549073,0.0008869205,0.0007194548,0.001699246],"category_scores_gemma":[0.002678104,0.0002421894,0.0009145344,0.000739345,0.0002762669,0.0005532417,0.0005039496,0.0007092789,0.0004204658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009948617,"about_ca_system_score_gemma":0.0007528645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02656873,"about_ca_topic_score_gemma":0.02928125,"domain_scores_codex":[0.9997513,0.00007892309,0.00001451188,0.00009669131,0.00002721959,0.00003135296],"domain_scores_gemma":[0.9994166,0.0002785223,0.0001013626,0.00003827074,0.0001152736,0.0000498987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.001143515,0.0003376842,0.113087,0.0001478919,0.0008870229,0.0003661184,0.00008743667,0.8011263,0.001439506,0.001438517,0.006347731,0.07359137],"study_design_scores_gemma":[0.0000241789,0.00006950271,0.01010463,0.00002490212,0.0001196152,0.00006188117,0.000009294608,0.9871511,0.0001512971,0.001921428,0.00035212,0.00001006866],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8604495,0.004329319,0.1182085,0.001253139,0.0001402212,0.0001654911,0.0100297,0.001585914,0.003838165],"genre_scores_gemma":[0.9857907,0.0003262154,0.009086795,0.00007971193,0.0000412348,0.00008472853,0.003598287,0.00002399481,0.0009683429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02656873,"threshold_uncertainty_score":0.05282819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03793421946344422,"score_gpt":0.321959860753268,"score_spread":0.2840256412898238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}