{"id":"W4404348923","doi":"10.1038/s41467-024-54194-1","title":"HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Institute of Botany, Chinese Academy of Sciences; National Institutes of Health; National Institute of General Medical Sciences; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China; Peking University; Foundation for the National Institutes of Health","keywords":"Biogenesis; Chloroplast; Gene; Nuclear gene; Photosynthesis; Computational biology; Biology; Genetics; Motif (music); Cell biology; Genome; Botany; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001249176,0.0003877852,0.0002352293,0.0002544752,0.0002137408,0.0002437608,0.0002378309,0.0002360883,0.002061595],"category_scores_gemma":[0.0001304141,0.0002334591,0.0003144533,0.000188103,0.0002764448,0.000157681,0.0004130433,0.0005565329,0.0004635467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004702366,"about_ca_system_score_gemma":0.0002266441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008097196,"about_ca_topic_score_gemma":0.001514425,"domain_scores_codex":[0.9998604,0.00001670051,0.00001522968,0.00003385725,0.0000382504,0.00003546758],"domain_scores_gemma":[0.9998019,0.00003194586,0.00005820457,0.00002794705,0.00001289306,0.00006715636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005578227,0.000008515452,0.0001072166,0.00001049031,0.000001796562,0.00001625106,0.000004583392,0.00001783443,0.9993876,0.00004596237,0.0000142486,0.0003296839],"study_design_scores_gemma":[0.0000152526,0.00008212219,0.01216231,0.000003812375,0.00001166906,0.0001563863,0.00002046219,0.001397678,0.9847131,0.00007656937,0.001352018,0.000008710907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946834,0.0003691283,0.002942822,0.00007248043,0.00003012451,0.00001617806,0.0005978519,0.0002171765,0.001070817],"genre_scores_gemma":[0.9950083,0.000136234,0.001857517,0.0000537513,0.000005837723,0.00001612067,0.0008309225,0.00008196055,0.002009379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002061595,"threshold_uncertainty_score":0.006896734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01211877898384137,"score_gpt":0.2642980171102777,"score_spread":0.2521792381264363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}