{"id":"W4404349215","doi":"10.1158/1538-8514.rnadrivers24-pr003","title":"Abstract PR003: Preventing and treating HPV-related Cancer with mRNA Therapy Expressing A DC-targeting Antigen","year":2024,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"iProgen Biotech (Canada)","funders":"","keywords":"Medicine; Cancer; Antigen; Cancer research; Immunology; Messenger RNA; Virology; Biology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009354587,0.0002463747,0.0001458149,0.0002263422,0.00009077825,0.0002235615,0.0001725783,0.0003169544,0.006276391],"category_scores_gemma":[0.00007284669,0.00006047992,0.0001962444,0.0001477604,0.0001201013,0.0001338055,0.000118711,0.000437487,0.001277013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002341764,"about_ca_system_score_gemma":0.0003472935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000849246,"about_ca_topic_score_gemma":0.001109024,"domain_scores_codex":[0.999954,0.000007786091,0.000002956803,0.0000071898,0.00001877989,0.000009226376],"domain_scores_gemma":[0.9999785,0.000003946916,0.000005033357,0.000002214066,0.000005399824,0.000004971434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006746649,0.0003768572,0.0005809675,0.0002989884,0.00001645294,0.0001937064,0.00003063017,0.0003528358,0.8967456,0.0006662864,0.005417062,0.09464592],"study_design_scores_gemma":[0.0002683743,0.004402424,0.005947448,0.00006403011,0.00006705071,0.00107536,0.00004797976,0.001471338,0.9095483,0.0002108182,0.07688135,0.00001552991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.876149,0.03298888,0.02023958,0.003508377,0.001424544,0.0008899029,0.002402347,0.001065056,0.06133237],"genre_scores_gemma":[0.9032184,0.01786678,0.01624165,0.0007313875,0.0002281135,0.0003071608,0.002246379,0.0001150225,0.05904496],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.006276391,"threshold_uncertainty_score":0.02099663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01857000272179574,"score_gpt":0.2936979135475358,"score_spread":0.2751279108257401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}