{"id":"W4404360795","doi":"10.3324/haematol.2024.285916","title":"Ixazomib, pomalidomide and dexamethasone in relapsed or refractory multiple myeloma characterized with high-risk cytogenetics: the IFM 2014-01 study","year":2024,"lang":"en","type":"article","venue":"Haematologica","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"National Cancer Institute","keywords":"Pomalidomide; Ixazomib; Dexamethasone; Multiple myeloma; Medicine; Oncology; Lenalidomide; Internal medicine; Refractory (planetary science); Cytogenetics; Carfilzomib; Biology; Genetics; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006523854,0.0003601642,0.0007850082,0.0002310153,0.0001846735,0.0001044829,0.0001828987,0.0001567107,0.0003659462],"category_scores_gemma":[0.0007914905,0.0001666394,0.00007521283,0.0003872492,0.0002536564,0.00007938452,0.0001502152,0.0005892309,0.0001819529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009291124,"about_ca_system_score_gemma":0.0001581342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006727003,"about_ca_topic_score_gemma":0.001056404,"domain_scores_codex":[0.9972513,0.0005510281,0.0004509761,0.0007165623,0.000466149,0.0005640099],"domain_scores_gemma":[0.9973757,0.001546317,0.0001140827,0.0006538162,0.0000617461,0.0002482959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0160563,0.001533753,0.93646,0.0002302464,0.0008234708,0.0178156,0.001524538,0.000002162682,0.003223263,0.00005387198,0.0003914021,0.02188541],"study_design_scores_gemma":[0.0147453,0.004348467,0.9738092,0.0002914389,0.0002772397,0.001083343,0.001156942,0.0006528215,0.002040903,0.00006047198,0.001275274,0.0002585388],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944193,0.001736152,0.00002749736,0.0008684463,0.00009064757,0.002491115,0.00004483988,0.0001699865,0.0001520518],"genre_scores_gemma":[0.9957057,0.0009264434,0.002038281,0.000109706,0.00006353668,0.0004871685,0.00003253095,0.00005159966,0.0005850964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03734928,"threshold_uncertainty_score":0.6795356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03519736241790303,"score_gpt":0.3047638499935024,"score_spread":0.2695664875755993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}