{"id":"W4404363619","doi":"10.1161/circ.150.suppl_1.4140254","title":"Abstract 4140254: Sex Influences Effects on Atherosclerosis in <i>TET2</i> -related Clonal Hematopoiesis of Indeterminate Potential and on Interleukin-1β Inhibition in Mice","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Haematopoiesis; Indeterminate; Interleukin; Immunology; Interleukin 6; Cytokine; Stem cell; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005576331,0.0005588388,0.0005201691,0.001076381,0.0003867596,0.0005929571,0.0005005004,0.0007913479,0.008117764],"category_scores_gemma":[0.000261518,0.0003722933,0.0007946433,0.0003996188,0.0006692628,0.0003068284,0.0004033885,0.001512167,0.001190472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000425334,"about_ca_system_score_gemma":0.0004080052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001355356,"about_ca_topic_score_gemma":0.002193289,"domain_scores_codex":[0.9992145,0.0001541639,0.00006658336,0.0002098329,0.0001539981,0.0002007909],"domain_scores_gemma":[0.9991923,0.0001141506,0.0002656358,0.00008956845,0.00005745018,0.0002809387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005217322,0.0005233555,0.003694882,0.00010243,0.0000588744,0.0002184804,0.0001041497,0.00008941942,0.9854542,0.0002816683,0.0006761858,0.003579007],"study_design_scores_gemma":[0.0008933225,0.007526018,0.1037257,0.00009309193,0.0004180014,0.001004339,0.0002928611,0.001175142,0.8724138,0.0003904336,0.0119946,0.000072645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887871,0.0007983274,0.001661307,0.0004382975,0.0001032037,0.00007742537,0.005839395,0.0001758143,0.002118963],"genre_scores_gemma":[0.972517,0.001012009,0.002605462,0.0009258534,0.00008498799,0.0004886695,0.0056003,0.0004486887,0.01631696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008117764,"threshold_uncertainty_score":0.02715665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005407576880088812,"score_gpt":0.2307598251904639,"score_spread":0.2253522483103751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}