{"id":"W4404363619","doi":"10.1161/circ.150.suppl_1.4140254","title":"Abstract 4140254: Sex Influences Effects on Atherosclerosis in <i>TET2</i> -related Clonal Hematopoiesis of Indeterminate Potential and on Interleukin-1β Inhibition in Mice","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Haematopoiesis; Indeterminate; Interleukin; Immunology; Interleukin 6; Cytokine; Stem cell; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000196924,0.0001468306,0.0001492178,0.0002349646,0.00002403689,0.00002880125,0.00003752596,0.0002546526,0.000006327202],"category_scores_gemma":[0.0000305653,0.0001562722,0.00005853369,0.0002220471,0.00004992287,0.00001981154,0.00002399369,0.0001420583,0.000004973931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008302525,"about_ca_system_score_gemma":0.00003679429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005365627,"about_ca_topic_score_gemma":0.0000535791,"domain_scores_codex":[0.998948,0.00006324868,0.000336324,0.0003602877,0.00015379,0.0001382955],"domain_scores_gemma":[0.9996871,0.00004142932,0.00009609517,0.0001215122,0.00002552845,0.00002835268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008680199,0.00004654494,0.008337269,0.0001638277,0.00002153182,0.000006534124,0.0002332067,0.01432811,0.9675384,0.00005415853,0.00001094998,0.009172628],"study_design_scores_gemma":[0.000632149,0.0001246797,0.4775184,0.0007153886,0.00001381215,0.00001033049,0.00001958939,0.003028721,0.5173533,0.0004216161,0.00001800191,0.0001440361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988789,0.000393063,0.00004806988,0.00008532516,0.0001912618,0.0002648278,0.00000773255,0.00001563498,0.0001152073],"genre_scores_gemma":[0.999676,0.00006454097,0.00001337733,0.00003577043,0.00006324088,0.00002122607,0.00009465402,0.00001990642,0.00001122081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4691812,"threshold_uncertainty_score":0.6372597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005407576880088812,"score_gpt":0.2307598251904639,"score_spread":0.2253522483103751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}