{"id":"W4404363721","doi":"10.1161/circ.150.suppl_1.4139912","title":"Abstract 4139912: Inflammatory biomarkers in people treated with tirzepatide living with overweight or obesity, without and with T2D: a post-hoc analysis from SURMOUNT-1 and SURMOUNT-2","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiovascular Disease and Adiposity","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Overweight; Post-hoc analysis; Obesity; Post hoc; Gerontology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00123902,0.0005771016,0.001347409,0.0003191269,0.0003004181,0.0003734621,0.0003909166,0.0004266912,0.003395833],"category_scores_gemma":[0.001422316,0.0002539021,0.002582193,0.0003201383,0.0002493701,0.0002803096,0.0005427294,0.0007082786,0.0002703283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003393031,"about_ca_system_score_gemma":0.0006956016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003850623,"about_ca_topic_score_gemma":0.006807013,"domain_scores_codex":[0.9993008,0.0002897781,0.00005313698,0.0001271732,0.0001150258,0.0001139847],"domain_scores_gemma":[0.9989146,0.0003580503,0.0002382471,0.0001335473,0.0001694629,0.0001861097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6318333,0.006172798,0.3050053,0.0008718931,0.00825962,0.0002960447,0.0005857989,0.0005952651,0.01611706,0.0000921406,0.001729183,0.02844163],"study_design_scores_gemma":[0.0137507,0.05998165,0.9158341,0.00003442207,0.004998188,0.0001467664,0.000321554,0.0009105316,0.002149948,0.00004854059,0.001779939,0.00004378148],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986336,0.0001807104,0.00008407187,0.0000209859,0.00001979576,0.0001292106,0.0007076696,0.000005196084,0.0002188631],"genre_scores_gemma":[0.9959376,0.0001140448,0.0003941859,0.00007268943,0.00002858341,0.0003541246,0.001944948,0.000005679778,0.001148198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003850623,"threshold_uncertainty_score":0.01136017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005620609372391885,"score_gpt":0.215800621649665,"score_spread":0.2101800122772731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}