{"id":"W4404374031","doi":"10.7554/elife.97100.2.sa2","title":"Reviewer #2 (Public review): Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Compute Canada","keywords":"Parvalbumin; Neuroscience; Synaptic membrane; Auditory cortex; Cortex (anatomy); Psychology; Biology; Chemistry; Membrane","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02949737,0.001688774,0.003567694,0.004449854,0.00280583,0.008799952,0.00603265,0.02104942,0.09683812],"category_scores_gemma":[0.1460709,0.00142022,0.003464814,0.002785057,0.002090026,0.004920834,0.004282507,0.007185735,0.04484177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006942003,"about_ca_system_score_gemma":0.0131114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003246402,"about_ca_topic_score_gemma":0.005130527,"domain_scores_codex":[0.9814301,0.004697483,0.003033992,0.002122961,0.007454771,0.001260701],"domain_scores_gemma":[0.7556278,0.01939216,0.01299563,0.005625028,0.1942214,0.01213809],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003572755,0.000004905915,0.00008038293,0.0009814869,0.00001740676,0.00002978403,0.00001413675,0.00001232968,0.00004704434,0.00006302352,0.9944615,0.004252317],"study_design_scores_gemma":[0.000314976,0.00007468661,0.001805802,0.004166944,0.0001340219,0.0003268498,0.0001317654,0.0001612972,0.0002588134,0.0008555584,0.9916928,0.00007638727],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"commentary","genre_scores_codex":[0.0003455596,0.01299066,0.000917275,0.3447677,0.6282616,0.001147509,0.003457022,0.0006881948,0.007424446],"genre_scores_gemma":[0.006201155,0.01692873,0.00173381,0.4534681,0.4509714,0.004949146,0.003441801,0.0009331508,0.0613727],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9705026,"threshold_uncertainty_score":0.3239558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05642920594554351,"score_gpt":0.3598012997029036,"score_spread":0.3033720937573601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}