{"id":"W4404401591","doi":"10.26434/chemrxiv-2024-swzp7","title":"Total Synthesis of (–)-Cordycicadin D and 3,4-trans-Cordycicadins A and B: Entry to the 3,4-trans-Fused Cordycicadin Framework","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Auckland","keywords":"Chemistry; Stereochemistry; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001027324,0.0005248259,0.0002364889,0.0002420738,0.0002011731,0.0003008477,0.0002082011,0.0002083067,0.001537733],"category_scores_gemma":[0.0001321255,0.000137183,0.0002470003,0.0003861497,0.0001315191,0.0002547323,0.0004052057,0.000467839,0.0008167276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004258704,"about_ca_system_score_gemma":0.0006572545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00139948,"about_ca_topic_score_gemma":0.001760748,"domain_scores_codex":[0.999921,0.000006650007,0.000009216847,0.00002128625,0.00001653288,0.00002530166],"domain_scores_gemma":[0.999936,0.000004095265,0.00001132077,0.000009746576,0.00001197451,0.00002695925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001692129,0.00005860778,0.000340042,0.000165251,0.00001789434,0.0003374311,0.00007894455,0.0009042629,0.9804311,0.0013194,0.00020531,0.01597243],"study_design_scores_gemma":[0.00003513341,0.0004581689,0.0009975052,0.00001636692,0.00002661851,0.0004195236,0.0000517471,0.001413181,0.9839702,0.0002757899,0.0123169,0.00001873294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634286,0.001627785,0.01784235,0.0001086805,0.00006211042,0.000178091,0.001141005,0.0003765187,0.01523487],"genre_scores_gemma":[0.9720702,0.001320208,0.01946113,0.00006194984,0.000006752479,0.00006777101,0.001003352,0.00005165417,0.005956988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537733,"threshold_uncertainty_score":0.005144238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139851480572846,"score_gpt":0.2564387340432398,"score_spread":0.2424535859859552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}