{"id":"W4404441033","doi":"10.1093/stmcls/sxae076","title":"Microglia in the spinal cord stem cell niche regulate neural precursor cell proliferation via soluble CD40 in response to myelin basic protein","year":2024,"lang":"en","type":"article","venue":"Stem Cells","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Stem Cell Network","keywords":"Neural stem cell; Biology; Myelin; Cell biology; Microglia; Spinal cord; Neuroscience; Myelin basic protein; Stem cell; Immunology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001252941,0.0002791047,0.000232603,0.0002449396,0.000212026,0.000365654,0.0001081805,0.0002114912,0.000856329],"category_scores_gemma":[0.0001195333,0.00009873193,0.0001897375,0.0001016726,0.0002783017,0.0001494201,0.0001934582,0.0003477479,0.0002890741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004259057,"about_ca_system_score_gemma":0.0003488345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009235141,"about_ca_topic_score_gemma":0.001716167,"domain_scores_codex":[0.9998073,0.00002539618,0.00001110318,0.00002244152,0.00007204542,0.00006186206],"domain_scores_gemma":[0.9999191,0.000009093739,0.00002185377,0.000004924857,0.00001523929,0.00002987737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009811325,0.000018411,0.0002099328,0.00003344518,0.000002629621,0.00006302627,0.00004443944,0.00005852227,0.9973848,0.000168114,0.00003660352,0.001881966],"study_design_scores_gemma":[0.00002142544,0.0002406634,0.009079381,0.00001798346,0.00001482286,0.0001744828,0.000125486,0.001173,0.9862595,0.0002463259,0.002643066,0.000004021415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939454,0.002522191,0.001398362,0.0001102467,0.00002844715,0.00001843029,0.000107003,0.00005903319,0.001810901],"genre_scores_gemma":[0.9942603,0.001403469,0.001535266,0.0000419934,0.00002131158,0.00003769398,0.0001021185,0.0000115022,0.002586341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009235141,"threshold_uncertainty_score":0.003090143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03090939485799696,"score_gpt":0.2581894282174234,"score_spread":0.2272800333594265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}