{"id":"W4404455231","doi":"10.25251/skin.8.supp.437","title":"Bimekizumab 4-year Maintenance of Responses in Week 16 Responders with Moderate to Severe Plaque Psoriasis: Results from the BE BRIGHT Open-label Extension Phase 3 Trial","year":2024,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"School of Medicine, Indiana University; Universidade de São Paulo; Manchester Biomedical Research Centre; Dalhousie University; National Institute for Health and Care Research","keywords":"Plaque psoriasis; Open label; Psoriasis; Medicine; Internal medicine; Dermatology; Clinical trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00442327,0.0008892709,0.002098304,0.0003039846,0.0004994658,0.001013254,0.0007692427,0.001274031,0.003709649],"category_scores_gemma":[0.001895743,0.0004833029,0.001827654,0.0003005372,0.0007156153,0.000957526,0.0004742024,0.003452833,0.000985387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005551007,"about_ca_system_score_gemma":0.001336543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006349509,"about_ca_topic_score_gemma":0.001096407,"domain_scores_codex":[0.9987698,0.0006919704,0.00005289962,0.0001156154,0.0001303226,0.0002393489],"domain_scores_gemma":[0.9982176,0.0003343911,0.0004578765,0.000192519,0.0001135587,0.0006840144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9312199,0.02580038,0.004608472,0.0003128388,0.0006889929,0.00006804281,0.0001279565,0.000403347,0.007777955,0.0001039005,0.002027952,0.02686016],"study_design_scores_gemma":[0.6363758,0.3325028,0.02611982,0.00005524032,0.0006673671,0.0001625224,0.00004922504,0.0005446456,0.001380589,0.0001822511,0.001928053,0.00003163704],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938657,0.002038847,0.0002295073,0.0003028309,0.0000856011,0.001026638,0.0009388239,0.00004343546,0.001468685],"genre_scores_gemma":[0.9916156,0.001147921,0.0007774173,0.0006184152,0.0002400635,0.001637627,0.001821032,0.00002223856,0.002119648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00442327,"threshold_uncertainty_score":0.0233928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2612660508904314,"score_gpt":0.4255791209063332,"score_spread":0.1643130700159018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}