{"id":"W4404467280","doi":"10.1164/rccm.202409-1681ed","title":"Best in Class: IgG as a Treatable Trait for Exacerbation Prevention in Chronic Obstructive Pulmonary Disease","year":2024,"lang":"en","type":"letter","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Medicine; Pulmonary disease; Exacerbation; Antibody; Intensive care medicine; Disease; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001782791,0.0006176258,0.001091697,0.0006722166,0.002867602,0.001622602,0.0009996673,0.03228744,0.00394406],"category_scores_gemma":[0.01173018,0.0004097719,0.001043165,0.0004681192,0.001509751,0.001332309,0.0006775057,0.01690688,0.002507493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003529208,"about_ca_system_score_gemma":0.003578039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00820599,"about_ca_topic_score_gemma":0.01508484,"domain_scores_codex":[0.9985521,0.0004555621,0.0001951009,0.0001574109,0.0003834596,0.0002563678],"domain_scores_gemma":[0.9964515,0.001945755,0.0001896194,0.0001129946,0.0004022583,0.0008979093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002041955,0.0002404343,0.009208859,0.00008663628,0.00006049791,0.02972434,0.00019478,0.0001821222,0.0006862664,0.006339807,0.9337676,0.0193045],"study_design_scores_gemma":[0.001099889,0.0006877928,0.02637465,0.00121736,0.0002774113,0.06034402,0.0008653321,0.004745515,0.001027767,0.02827866,0.874907,0.0001746285],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003967937,0.001863349,0.0002466429,0.9607233,0.01920699,0.00002785133,0.0001032616,0.00004768109,0.01381305],"genre_scores_gemma":[0.03580259,0.001791649,0.0007138031,0.8606108,0.08281878,0.00006539805,0.0001041925,0.00005175306,0.01804104],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03228744,"threshold_uncertainty_score":0.02560627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02652199526376868,"score_gpt":0.3478223781546298,"score_spread":0.3213003828908611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}