{"id":"W4404502560","doi":"10.3390/vaccines12111290","title":"Nanoparticles as Delivery Systems for Antigenic Saccharides: From Conjugation Chemistry to Vaccine Design","year":2024,"lang":"en","type":"review","venue":"Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Université du Québec à Montréal","keywords":"Immune system; Antigen; Glycoconjugate; Chemistry; Epitope; Glycan; Biology; Immunology; Biochemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006090922,0.0007545412,0.0009423578,0.0009365563,0.0001533147,0.0007918012,0.0005990489,0.0008782754,0.0008598529],"category_scores_gemma":[0.0003124254,0.0004401908,0.0004676467,0.0006559904,0.0004985905,0.001220669,0.0004796965,0.001282336,0.0008953417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006782237,"about_ca_system_score_gemma":0.0004001208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000290193,"about_ca_topic_score_gemma":0.0002901783,"domain_scores_codex":[0.9997682,0.00005397615,0.00002331396,0.0000554336,0.00007309076,0.00002592618],"domain_scores_gemma":[0.9999202,0.00002725351,0.00001507631,0.000004894341,0.0000238051,0.000008706163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001656314,0.0002606806,0.000235777,0.01512012,0.0001474449,0.0005697606,0.0003152434,0.004557573,0.4970179,0.03861331,0.005679457,0.437317],"study_design_scores_gemma":[0.00006462374,0.001043288,0.0007417391,0.001506034,0.0001479957,0.001685563,0.0000974544,0.003872779,0.2395571,0.01204059,0.7391322,0.0001106809],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01351446,0.9410062,0.03808608,0.001122967,0.000764728,0.0001586804,0.00009108912,0.0001831144,0.005072707],"genre_scores_gemma":[0.04892346,0.9076973,0.03488802,0.001020143,0.0005957017,0.0002746136,0.0002162777,0.00007800749,0.006306396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009423578,"threshold_uncertainty_score":0.0049209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04356842787710201,"score_gpt":0.3102175893085086,"score_spread":0.2666491614314065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}