{"id":"W4404502560","doi":"10.3390/vaccines12111290","title":"Nanoparticles as Delivery Systems for Antigenic Saccharides: From Conjugation Chemistry to Vaccine Design","year":2024,"lang":"en","type":"review","venue":"Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Université du Québec à Montréal","keywords":"Immune system; Antigen; Glycoconjugate; Chemistry; Epitope; Glycan; Biology; Immunology; Biochemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003961658,0.0006361112,0.001679642,0.0002039247,0.0002058729,0.000124109,0.0005240042,0.0007035622,0.0004885556],"category_scores_gemma":[0.000230026,0.0004782564,0.0005259542,0.0003272496,0.00001846519,0.00009972182,0.0001112274,0.0003084794,0.003120393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001025911,"about_ca_system_score_gemma":0.0003796954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002699073,"about_ca_topic_score_gemma":0.000002601536,"domain_scores_codex":[0.9974973,0.0003333191,0.0009509411,0.0006901519,0.00004333253,0.0004849822],"domain_scores_gemma":[0.9978981,0.001029281,0.000305143,0.0005947218,0.000138494,0.00003427728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002032232,0.0001670837,0.000002475948,0.01389484,0.005132171,0.00001872155,0.0003513644,0.0000136726,0.333161,0.00008118421,0.0518676,0.5932777],"study_design_scores_gemma":[0.0006366237,0.0002096214,0.000002226837,0.007886972,0.001666639,0.0001091307,0.0000799511,0.000004259833,0.03389788,0.00004784905,0.954927,0.0005318731],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003529829,0.9912191,0.0002743432,0.0000501569,0.002292443,0.002064289,0.000343067,0.0002121671,0.00001462293],"genre_scores_gemma":[0.0004341966,0.988103,0.00006903128,0.00005919173,0.0002417365,0.0008434454,0.0006947853,0.0001199924,0.009434631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9030594,"threshold_uncertainty_score":0.9997669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04356842787710201,"score_gpt":0.3102175893085086,"score_spread":0.2666491614314065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}