{"id":"W4404502581","doi":"10.1080/22221751.2024.2432353","title":"Evaluation of waning of IgG antibody responses after rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccines: a modelling study from the PREVAC randomized trial","year":2024,"lang":"en","type":"article","venue":"Emerging Microbes & Infections","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"European and Developing Countries Clinical Trials Partnership; Janssen Alzheimer Immunotherapy Research And Development; Janssen Biotech; Innovative Medicines Initiative; Université de Bordeaux; Ministère de l'Enseignement Supérieur et de la Recherche; Center for Biomedical Informatics and Information Technology, National Cancer Institute; European Commission; Frederick National Laboratory for Cancer Research; Institut National de la Santé et de la Recherche Médicale; Bavarian Nordic; Merck Sharp and Dohme; Centre National de la Recherche Scientifique; National Cancer Institute; European Federation of Pharmaceutical Industries and Associations; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Horizon 2020; London School of Hygiene and Tropical Medicine","keywords":"Ebola vaccine; Medicine; Virology; Ebola virus; Antibody; Antibody response; Disease; Immunology; Ebolavirus; Virus; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02958839,0.002715764,0.004824856,0.0004539194,0.0002553831,0.001437576,0.001658971,0.0022869,0.003166051],"category_scores_gemma":[0.01813782,0.001057097,0.008590848,0.0005255503,0.0009116508,0.001421511,0.0009240046,0.003067494,0.0005844421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001163169,"about_ca_system_score_gemma":0.002292128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001064448,"about_ca_topic_score_gemma":0.0007423593,"domain_scores_codex":[0.9877793,0.009668262,0.0004459109,0.0009238474,0.0005397436,0.0006429444],"domain_scores_gemma":[0.9870681,0.007550187,0.002561955,0.00165877,0.0005043127,0.0006566604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.9580863,0.003935493,0.003420778,0.00144856,0.009106128,0.00006266,0.00009343484,0.005864035,0.003770735,0.0002611329,0.0005483897,0.0134025],"study_design_scores_gemma":[0.3554391,0.5814783,0.01516697,0.0002538957,0.01855747,0.0001752571,0.00006314776,0.01961143,0.005312896,0.001325345,0.002506064,0.0001101193],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760267,0.009832548,0.006266155,0.0005854699,0.0003564723,0.003524216,0.001976975,0.0001823141,0.001248981],"genre_scores_gemma":[0.9882009,0.001845874,0.00285168,0.0002802184,0.0001437584,0.00367266,0.001674921,0.00004994488,0.001280157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02958839,"threshold_uncertainty_score":0.1564802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04169267854866104,"score_gpt":0.3867564232231482,"score_spread":0.3450637446744871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}