{"id":"W4404511815","doi":"10.1002/cbic.202400767","title":"Auto‐Deactivation of BODIPY‐Derived Type I Photosensitizer Post Photodynamic Therapy under Hypoxia","year":2024,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Education and Child Care","funders":"National Natural Science Foundation of China","keywords":"Photosensitizer; Photodynamic therapy; Chemistry; Reactive oxygen species; BODIPY; Photochemistry; HeLa; Biophysics; Mitochondrion; Redox; Biochemistry; In vitro; Biology; Fluorescence; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005787789,0.000180119,0.0001396587,0.00005631843,0.00006918752,0.00009759574,0.0001122116,0.0001873071,0.0007604274],"category_scores_gemma":[0.00005954749,0.00006458149,0.0001111104,0.00007436955,0.00009304393,0.0001533426,0.0001101668,0.000191355,0.0001404914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001436664,"about_ca_system_score_gemma":0.00007929358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003058886,"about_ca_topic_score_gemma":0.0002556086,"domain_scores_codex":[0.9999583,0.00000355991,0.000002063637,0.00001239235,0.00000930885,0.00001441914],"domain_scores_gemma":[0.99997,0.000005722528,0.00001009512,0.000004804407,0.000004466692,0.000004985569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002648345,0.00000396616,0.00005811063,0.00002504869,0.000001689089,0.00002327436,0.000007175749,0.00004305696,0.9991511,0.00003464525,0.00002215211,0.0006034136],"study_design_scores_gemma":[0.000002666051,0.00005225296,0.0006867455,0.000001139423,0.000002336058,0.00005008091,0.000003807407,0.0003349192,0.9984936,0.000009464519,0.0003620277,0.00000105351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948066,0.0008578291,0.003190683,0.00003899814,0.00001452769,0.00001546598,0.0000969688,0.0000566689,0.0009221388],"genre_scores_gemma":[0.9971858,0.0003407697,0.001060187,0.00002732171,0.000003044681,0.00001678836,0.00009904657,0.0000107957,0.001256156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007604274,"threshold_uncertainty_score":0.002543926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009954141793591529,"score_gpt":0.2196093331145105,"score_spread":0.209655191320919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}