{"id":"W4404521637","doi":"10.1371/journal.ppat.1012735","title":"The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence","year":2024,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; Ministry of Science and ICT, South Korea; Canadian Institutes of Health Research; National Research Foundation; Canadian Institute for Advanced Research","keywords":"Biology; Protein subunit; Protein phosphatase 2; Cryptococcus neoformans; Heterotrimeric G protein; Virulence; Fungal protein; Mutant; Genetics; Cell biology; Gene; Signal transduction; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000710043,0.0004340165,0.0001669851,0.0003083798,0.000194721,0.0003980683,0.0001859309,0.0002119064,0.0008059953],"category_scores_gemma":[0.0001256258,0.0001613326,0.000107737,0.0001919797,0.0001940532,0.0001623444,0.0004167102,0.0002796753,0.0003845697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004456643,"about_ca_system_score_gemma":0.0002332931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001911081,"about_ca_topic_score_gemma":0.001953173,"domain_scores_codex":[0.9998593,0.00001302821,0.00000875619,0.00003162127,0.00004864752,0.00003871002],"domain_scores_gemma":[0.999884,0.000007817323,0.00003791795,0.0000116464,0.00001589127,0.00004281108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006126358,0.0000104402,0.001158986,0.00001395468,0.000002147856,0.00004968957,0.00001234945,0.00006165417,0.9972175,0.00005796505,0.00006071534,0.001293369],"study_design_scores_gemma":[0.00001872821,0.0001576841,0.09962802,0.00001216439,0.00001604843,0.0008269118,0.0001968821,0.004521492,0.8911651,0.0001939679,0.003248061,0.00001496754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970537,0.0005550349,0.0008180912,0.0000452259,0.00000583102,0.000008762177,0.0003549755,0.00009022949,0.001068143],"genre_scores_gemma":[0.9979684,0.0001435749,0.0004549771,0.00001905408,0.000001580656,0.000005149905,0.0003245821,0.00001351608,0.001069168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001911081,"threshold_uncertainty_score":0.003799975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06710082110940258,"score_gpt":0.2855168213683826,"score_spread":0.2184160002589801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}