{"id":"W4404528858","doi":"10.1093/braincomms/fcae414","title":"Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders","year":2024,"lang":"en","type":"article","venue":"Brain Communications","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Horizon 2020 Framework Programme; University Hospital Foundation; Japan Fisheries Research and Education Agency; Skånes universitetssjukhus; Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse; Cure Alzheimer's Fund; Australian Government; Vetenskapsrådet; Science for Life Laboratory; Kirsten og Freddy Johansens Fond; Parkinsonfonden; Hjärnfonden; National Institute on Aging; Alzheimer's Association; Knut och Alice Wallenbergs Stiftelse; Lunds Universitet; GHR Foundation","keywords":"Biomarker; Medicine; Neuroscience; Internal medicine; Bioinformatics; Psychology; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003061572,0.0001206461,0.0001547642,0.00008444152,0.0002444118,0.00005578856,0.0001952731,0.00005791205,0.00004224457],"category_scores_gemma":[0.0001946305,0.00009763593,0.0001331733,0.0002394716,0.0001489159,0.00006952688,0.00009860901,0.0001333993,0.0000860803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003685318,"about_ca_system_score_gemma":0.00008163687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001864363,"about_ca_topic_score_gemma":0.00009807498,"domain_scores_codex":[0.9992412,0.00005545452,0.0001877297,0.0002167964,0.00009213023,0.0002066993],"domain_scores_gemma":[0.9985245,0.0004798447,0.00002931775,0.0008341016,0.00003055031,0.0001016137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006688069,0.002254909,0.006018209,0.0002271934,0.001117102,0.00005728715,0.0008104749,0.000003983099,0.01105443,0.0756439,0.08762053,0.8145232],"study_design_scores_gemma":[0.00191546,0.0006608464,0.09178936,0.0001351495,0.0002516348,0.00002469363,0.00009690695,0.00856601,0.00002262973,0.02453527,0.8718003,0.0002017611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.368129,0.05866848,0.004168394,0.5370851,0.0002655686,0.00305588,0.0001897228,0.0007785117,0.02765931],"genre_scores_gemma":[0.9836905,0.008319873,0.00193795,0.004362346,0.00001689966,0.0002908277,0.0001992656,0.00003142755,0.001150913],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8143214,"threshold_uncertainty_score":0.3981478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04140702068957956,"score_gpt":0.3483338101895859,"score_spread":0.3069267895000063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}