{"id":"W4404528858","doi":"10.1093/braincomms/fcae414","title":"Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders","year":2024,"lang":"en","type":"article","venue":"Brain Communications","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Horizon 2020 Framework Programme; University Hospital Foundation; Japan Fisheries Research and Education Agency; Skånes universitetssjukhus; Konung Gustaf V:s och Drottning Victorias Frimurarestiftelse; Cure Alzheimer's Fund; Australian Government; Vetenskapsrådet; Science for Life Laboratory; Kirsten og Freddy Johansens Fond; Parkinsonfonden; Hjärnfonden; National Institute on Aging; Alzheimer's Association; Knut och Alice Wallenbergs Stiftelse; Lunds Universitet; GHR Foundation","keywords":"Biomarker; Medicine; Neuroscience; Internal medicine; Bioinformatics; Psychology; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006427535,0.0005105077,0.0005156266,0.0006514849,0.0002040323,0.0008214024,0.0002695568,0.0003588368,0.001415574],"category_scores_gemma":[0.0008268601,0.0001183676,0.0003159278,0.0004337074,0.0002567667,0.0002163666,0.0002747217,0.0004439955,0.0002550086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004216227,"about_ca_system_score_gemma":0.0002810894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00209282,"about_ca_topic_score_gemma":0.001919705,"domain_scores_codex":[0.9997942,0.00005777706,0.00002120563,0.00005353487,0.00005788174,0.00001540677],"domain_scores_gemma":[0.9994164,0.0001281616,0.0002242733,0.0000316876,0.0001286886,0.00007088543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003923397,0.0002170319,0.8496614,0.0008525345,0.0009113817,0.001816894,0.0001740883,0.0003388723,0.07401367,0.0003437444,0.002101738,0.06564528],"study_design_scores_gemma":[0.0001040613,0.001486838,0.977085,0.0001825992,0.0003894354,0.002400703,0.0002591731,0.001223687,0.01193611,0.000734916,0.004168744,0.00002881852],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9390836,0.0552681,0.00144726,0.0006913437,0.0001838622,0.00005528163,0.001499146,0.0000661343,0.001705177],"genre_scores_gemma":[0.99238,0.00471893,0.001316699,0.0001767513,0.00007283028,0.00002136129,0.000486032,0.000005662966,0.0008216098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00209282,"threshold_uncertainty_score":0.004735589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04140702068957956,"score_gpt":0.3483338101895859,"score_spread":0.3069267895000063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}