{"id":"W4404538329","doi":"10.1080/10428194.2024.2430703","title":"Severe toxicity, but long-term persistence of CAR T cells after immune checkpoint inhibitors in large B-cell lymphoma","year":2024,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute; National Institutes of Health","keywords":"Persistence (discontinuity); Lymphoma; Toxicity; Term (time); Immune system; Immune checkpoint; Cancer research; Biology; Immunology; Medicine; Immunotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001740451,0.0005225373,0.001045479,0.0003807039,0.0005699809,0.001385928,0.001005179,0.003411881,0.001944947],"category_scores_gemma":[0.006816022,0.0002648257,0.0004879292,0.0003568745,0.0008094531,0.001073094,0.0002164904,0.005425451,0.001586707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008568497,"about_ca_system_score_gemma":0.0004567526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004748975,"about_ca_topic_score_gemma":0.001167813,"domain_scores_codex":[0.9994165,0.0001404077,0.0001145115,0.00009064225,0.0001635156,0.00007450292],"domain_scores_gemma":[0.9960459,0.002579215,0.0003291165,0.0001224031,0.0006585099,0.0002648319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002019054,0.0001345423,0.003253869,0.001064712,0.0002168014,0.01355065,0.0001013405,0.0003050031,0.003104993,0.002762683,0.82643,0.1470563],"study_design_scores_gemma":[0.0004838666,0.0009973194,0.01017197,0.0006237808,0.0005564179,0.04122595,0.0001676866,0.001233039,0.004652545,0.003625675,0.9361765,0.00008515727],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.02115397,0.1241212,0.002197259,0.5337266,0.309292,0.00005524093,0.0004544026,0.0002115486,0.008787888],"genre_scores_gemma":[0.106756,0.06094677,0.001053787,0.2452571,0.5654485,0.00005599543,0.0003058391,0.0001287671,0.02004728],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003411881,"threshold_uncertainty_score":0.009204507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144650995148856,"score_gpt":0.2485690102953221,"score_spread":0.2371225003438335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}