{"id":"W4404564918","doi":"10.51731/cjht.2024.1029","title":"Ciltacabtagene Autoleucel (Carvykti)","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lenalidomide; Medicine; Chimeric antigen receptor; Drug; Refractory (planetary science); Multiple myeloma; Disease; Thalidomide; Internal medicine; Oncology; Intensive care medicine; Pharmacology; Immunotherapy; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001013233,0.0001325622,0.0004136001,0.001401327,0.0001382592,0.00007491403,0.0002950783,0.000187854,0.0007984269],"category_scores_gemma":[0.0003963135,0.0001059619,0.0001509453,0.000701016,0.0002418381,0.00009394214,0.00002180832,0.001017353,0.0000570701],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00104458,"about_ca_system_score_gemma":0.008545843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002547982,"about_ca_topic_score_gemma":0.001346178,"domain_scores_codex":[0.9983486,0.00004437942,0.0005151528,0.0001670324,0.0003044099,0.0006204282],"domain_scores_gemma":[0.999109,0.00007329119,0.00009990011,0.0003141703,0.0001769485,0.0002267061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001849464,0.000008928655,0.0007753444,0.0002960005,0.00009413705,0.001837015,0.0002198441,0.000003157025,0.002454745,0.0009878151,0.0241357,0.9691688],"study_design_scores_gemma":[0.0003424607,0.0007166202,0.001915344,0.0006525581,0.00001891708,0.002398851,0.001154814,0.00008318967,0.003702682,0.001945543,0.9869679,0.000101116],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1882012,0.5416071,0.0005970121,0.259985,0.001826172,0.0006900982,0.00004269116,0.0007032985,0.006347418],"genre_scores_gemma":[0.9931344,0.00228246,0.0006320052,0.0006149004,0.00006000173,0.00000519022,0.000002527095,0.00003501886,0.003233444],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9690677,"threshold_uncertainty_score":0.9970748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05463637822091671,"score_gpt":0.3559239970667272,"score_spread":0.3012876188458105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}