{"id":"W4404564918","doi":"10.51731/cjht.2024.1029","title":"Ciltacabtagene Autoleucel (Carvykti)","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lenalidomide; Medicine; Chimeric antigen receptor; Drug; Refractory (planetary science); Multiple myeloma; Disease; Thalidomide; Internal medicine; Oncology; Intensive care medicine; Pharmacology; Immunotherapy; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004058954,0.0003690496,0.0007108559,0.0008872519,0.0004126207,0.00125371,0.0005527296,0.0008261317,0.02574857],"category_scores_gemma":[0.0007027351,0.0001448045,0.0005225034,0.0005450394,0.0003085228,0.0005389207,0.0007168725,0.002127723,0.0101927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001549389,"about_ca_system_score_gemma":0.0022705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006536763,"about_ca_topic_score_gemma":0.01276381,"domain_scores_codex":[0.9996409,0.00003366743,0.00002217067,0.00005864234,0.0001487235,0.00009588226],"domain_scores_gemma":[0.9996612,0.0000371499,0.00004791187,0.00002393898,0.00006312574,0.0001666322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004460047,0.0007968039,0.003022309,0.0009673725,0.0001319938,0.001325624,0.00008232513,0.0005301689,0.03223934,0.004793738,0.1862383,0.7654121],"study_design_scores_gemma":[0.005308352,0.002630637,0.008050106,0.0002789702,0.0001300977,0.005145971,0.00004169409,0.001091184,0.01636216,0.0009305175,0.9599905,0.00003973287],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.2379903,0.2779853,0.01424196,0.02740525,0.008126028,0.002843891,0.01513536,0.01324936,0.4030226],"genre_scores_gemma":[0.6738033,0.04675014,0.01081694,0.01470554,0.001460978,0.0009155716,0.02339872,0.0008035644,0.2273452],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.02574857,"threshold_uncertainty_score":0.08613759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05463637822091671,"score_gpt":0.3559239970667272,"score_spread":0.3012876188458105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}