{"id":"W4404573127","doi":"10.1146/annurev-med-070623-045906","title":"CD70: An Emerging Anticancer Target in Renal Cell Carcinoma and Beyond","year":2024,"lang":"en","type":"review","venue":"Annual Review of Medicine","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Chimeric antigen receptor; Cancer research; Immune system; Medicine; Antigen; Renal cell carcinoma; Antibody; Monoclonal antibody; Immunology; Immunotherapy; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004094693,0.0005968311,0.001081992,0.00174129,0.0002319638,0.0008938254,0.0006096686,0.0009775651,0.004031781],"category_scores_gemma":[0.0003055569,0.0001888624,0.0003746977,0.001670962,0.000333019,0.001188102,0.0005974419,0.001636124,0.002666783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005288346,"about_ca_system_score_gemma":0.0008560503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008600685,"about_ca_topic_score_gemma":0.00190983,"domain_scores_codex":[0.999891,0.00001883296,0.00001026425,0.00001764567,0.00004440502,0.00001771691],"domain_scores_gemma":[0.9998726,0.00004280038,0.00001927463,0.00000370325,0.00004012829,0.0000214739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007742704,0.00006599986,0.00009952158,0.009735004,0.00004455718,0.0001722834,0.00004775449,0.0003104113,0.002715303,0.004214089,0.0325399,0.9499778],"study_design_scores_gemma":[0.00001412006,0.00009339528,0.0003579082,0.001518696,0.00004213177,0.0006875701,0.00003520748,0.00006909896,0.0003566989,0.001333904,0.9954809,0.00001033333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001204594,0.9983198,0.00008629418,0.000296214,0.00017357,0.00000385613,0.00001342558,0.000007884396,0.0009785421],"genre_scores_gemma":[0.0006681479,0.9978398,0.0001380901,0.0002635072,0.0001658227,0.000006100791,0.00002965861,0.000001494446,0.000887408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004031781,"threshold_uncertainty_score":0.01348764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04943790490968927,"score_gpt":0.4245513748813523,"score_spread":0.375113469971663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}