{"id":"W4404575187","doi":"10.1097/hep.0000000000001163","title":"Outcome and management of patients with hepatocellular carcinoma who achieved a complete response to immunotherapy-based systemic therapy","year":2024,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Toronto General Hospital","funders":"","keywords":"Hepatocellular carcinoma; Medicine; Immunotherapy; Systemic therapy; Internal medicine; Oncology; Complete response; Outcome (game theory); Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003083138,0.0003182262,0.0007161663,0.0003446489,0.00006428173,0.0000237315,0.0001098845,0.0001241298,0.00007097775],"category_scores_gemma":[0.000006384125,0.0002321524,0.0001401662,0.0003755532,0.0001102888,0.0000400604,0.00004131072,0.0001357918,0.00003472612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001017179,"about_ca_system_score_gemma":0.00009096241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006148965,"about_ca_topic_score_gemma":0.000003190631,"domain_scores_codex":[0.9981273,0.0002523261,0.0004732991,0.0005049742,0.0002864629,0.0003556686],"domain_scores_gemma":[0.9990176,0.0001472092,0.00007194898,0.0004939715,0.0001043051,0.0001649836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008995986,0.0001938567,0.9829573,0.0008342915,0.0004758341,0.0009752046,0.0003370089,2.883635e-7,0.002049118,0.0002035543,0.00005775676,0.002919783],"study_design_scores_gemma":[0.009198778,0.004092004,0.9623768,0.0006992065,0.000357816,0.0001097191,0.0000705874,0.008892089,0.002165923,0.00001458819,0.01161436,0.0004081515],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915501,0.004449557,0.0005593094,0.001017118,0.0001039974,0.0020623,0.00006431956,0.0001064454,0.00008688486],"genre_scores_gemma":[0.9976255,0.0001312739,0.001129518,0.0005350769,0.00001435707,0.0002417576,0.0000744542,0.00006779861,0.000180287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02058055,"threshold_uncertainty_score":0.94669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04764592593813469,"score_gpt":0.2602757513383878,"score_spread":0.2126298254002531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}