{"id":"W4404624800","doi":"10.1016/j.bbih.2024.100907","title":"Immune cells and the trajectories of depression, anxiety, and cognitive function among people with amyotrophic lateral sclerosis","year":2024,"lang":"en","type":"article","venue":"Brain Behavior & Immunity - Health","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"H2020 European Research Council; European Research Council; Centers for Disease Control and Prevention; Vetenskapsrådet","keywords":"Amyotrophic lateral sclerosis; Depression (economics); Anxiety; Immune system; Cognition; Psychology; Multiple sclerosis; Clinical psychology; Medicine; Neuroscience; Psychiatry; Disease; Internal medicine; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004520484,0.0002429008,0.0002462258,0.0005068062,0.0004430887,0.000783376,0.0002222501,0.0003712598,0.0007296469],"category_scores_gemma":[0.001225583,0.0002446775,0.0004390322,0.0006013145,0.0001808926,0.000322254,0.0004500435,0.0005099399,0.0001846371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003153229,"about_ca_system_score_gemma":0.0002819005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01356972,"about_ca_topic_score_gemma":0.01372488,"domain_scores_codex":[0.9997744,0.00005732461,0.00002095313,0.00005415824,0.00002764837,0.00006547032],"domain_scores_gemma":[0.9996271,0.0000512288,0.000140113,0.00003898304,0.0000477801,0.00009467247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001062375,0.00003154248,0.9986852,0.000003942022,0.00003757156,0.00002928307,0.00008809339,0.00004907411,0.0001093306,0.00001132787,0.00005392801,0.0007945421],"study_design_scores_gemma":[0.00000622457,0.00008538897,0.9991745,0.000005301413,0.00002604547,0.00006247023,0.0002044659,0.0002734858,0.00002966166,0.00004533023,0.00008372765,0.000003312743],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995346,0.00007670218,0.00004348586,0.00002240521,0.000002719129,0.000003815024,0.0002293427,0.000001561425,0.00008536086],"genre_scores_gemma":[0.9994993,0.00004635367,0.0000433138,0.00001499381,0.000002721824,0.000006580276,0.0002560355,7.352161e-7,0.0001300024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01356972,"threshold_uncertainty_score":0.02698147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0226401847795058,"score_gpt":0.2897206797050624,"score_spread":0.2670804949255566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}