{"id":"W4404634272","doi":"10.1016/j.jtho.2024.11.016","title":"Differentiating Separate Primary Lung Adenocarcinomas From Intrapulmonary Metastases With Emphasis on Pathological and Molecular Considerations: Recommendations From the International Association for the Study of Lung Cancer Pathology Committee","year":2024,"lang":"en","type":"review","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; Institut universitaire de cardiologie et de pneumologie de Québec; Sunnybrook Health Science Centre","funders":"Chugai Pharmaceutical; Genentech; Taipei Veterans General Hospital; Daiichi-Sankyo; University of Glasgow; Cancer Research UK; Novocure; Regeneron Pharmaceuticals; EMD Serono; International Association for the Study of Lung Cancer; Daiichi Sankyo Europe; Sanofi; G1 Therapeutics; Amgen; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Pathological; Pathology; Lung; Molecular pathology; Adenocarcinoma; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005574591,0.0009983749,0.004438712,0.003609203,0.0004480473,0.002429082,0.002963966,0.002150084,0.001569106],"category_scores_gemma":[0.004516116,0.0005726945,0.002265726,0.002380363,0.0009853265,0.002555155,0.0010958,0.00430642,0.001404983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001538072,"about_ca_system_score_gemma":0.005653048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004387066,"about_ca_topic_score_gemma":0.01152061,"domain_scores_codex":[0.9989904,0.0002139661,0.0003133228,0.0001223853,0.0003072968,0.00005267884],"domain_scores_gemma":[0.9966589,0.001340377,0.0003857042,0.00007432301,0.001382893,0.0001578641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001343498,0.00006824033,0.0008328087,0.02662208,0.000413436,0.0002482228,0.00006649745,0.0002326582,0.0009239668,0.002010896,0.06902788,0.899419],"study_design_scores_gemma":[0.0001326422,0.0001649941,0.004048847,0.04411918,0.001631719,0.001831498,0.0001900226,0.0002278341,0.0006099936,0.003176753,0.9437947,0.00007178792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009838986,0.9955328,0.0003693843,0.002638567,0.0007692068,0.00002886244,0.00007036362,0.000009911989,0.0004825425],"genre_scores_gemma":[0.0007178443,0.9944594,0.001797951,0.002073992,0.0004102397,0.00003495218,0.0001548523,0.000004035803,0.000346724],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005574591,"threshold_uncertainty_score":0.02948159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05737388833707415,"score_gpt":0.4541069086072013,"score_spread":0.3967330202701272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}