{"id":"W4404701273","doi":"10.1242/jcs.262177","title":"Phosphorylation on serine 72 modulates Rab7A palmitoylation and retromer recruitment","year":2024,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université du Québec à Montréal; Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Canada Foundation for Innovation; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research; Armand-Frappier Foundation; McGill University","keywords":"Endosome; Palmitoylation; Retromer; Biology; Cell biology; Phosphorylation; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005071916,0.00005925835,0.00005998075,0.00007567496,0.00006093724,0.00005463676,0.00007723527,0.00003889942,0.00001575724],"category_scores_gemma":[0.00001183922,0.00004621883,0.00003919203,0.0001381349,0.00006729082,0.00001692376,0.00001379888,0.00006932452,0.000002266691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002020165,"about_ca_system_score_gemma":0.00006169315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001057324,"about_ca_topic_score_gemma":0.000001070956,"domain_scores_codex":[0.9993645,0.000009975437,0.0001570308,0.0001398418,0.0002285832,0.0001000961],"domain_scores_gemma":[0.9997249,0.000005496936,0.00006373562,0.00007353423,0.00007290665,0.00005944415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003629933,0.00001350617,0.0005311455,0.00001196771,0.000003967127,0.000005794427,0.0000656382,0.0001930741,0.994456,0.00006695532,0.00003038961,0.00458526],"study_design_scores_gemma":[0.0001865817,0.000528755,0.01556668,0.00004385758,0.00001453934,0.00002840739,0.00003561414,0.001717246,0.9619113,0.0002474952,0.01963801,0.0000815657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926438,0.001491388,0.004522275,0.0001320504,0.0003172195,0.00007239143,9.502276e-7,0.000002998631,0.0008168912],"genre_scores_gemma":[0.9983754,0.0006905135,0.0004245557,0.00003054017,0.0001331779,8.92764e-7,0.00001730094,0.000004871162,0.0003227829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03254477,"threshold_uncertainty_score":0.1884749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628681210922828,"score_gpt":0.2579799524141235,"score_spread":0.2416931403048952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}