{"id":"W4404705049","doi":"10.34172/bi.30573","title":"Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity","year":2024,"lang":"en","type":"review","venue":"Bioimpacts","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Nanomedicine; Nanocarriers; Drug delivery; Biodistribution; ADME; Nanotechnology; Medicine; Drug; Pharmacology; Risk analysis (engineering); Chemistry; Materials science; Nanoparticle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007987119,0.0005597249,0.001402703,0.0003794024,0.00008606847,0.0003072885,0.0003905352,0.000217682,0.00005127586],"category_scores_gemma":[0.0002318947,0.0004006605,0.000174461,0.0003878526,0.000117127,0.0005337555,0.0002904461,0.0001303229,0.0002391927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002777388,"about_ca_system_score_gemma":0.0003600224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003461002,"about_ca_topic_score_gemma":0.00005257054,"domain_scores_codex":[0.9971561,0.0002889267,0.0008854263,0.0008061935,0.0003022185,0.0005611414],"domain_scores_gemma":[0.998471,0.0005214127,0.000312716,0.0003710686,0.00007266909,0.0002511244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001054638,0.0001307928,8.761485e-7,0.02739238,0.00002153681,0.00005792177,0.00043009,0.000005073945,0.134871,0.00005574604,0.002185342,0.8347438],"study_design_scores_gemma":[0.0004210944,0.0001225286,5.753594e-7,0.009983865,0.0004490865,0.00001331121,0.0000103006,0.00005677533,0.1314663,0.000701997,0.8562375,0.0005367517],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0910743,0.9052479,0.00001401014,0.0000195347,0.001725148,0.00156374,0.0002040829,0.0001116592,0.00003966175],"genre_scores_gemma":[0.009856064,0.9885661,0.000847735,0.00004914449,0.0003218279,0.0001931112,0.00004452989,0.00007714095,0.00004437197],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8540521,"threshold_uncertainty_score":0.9998446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03208746612419353,"score_gpt":0.3419517232774589,"score_spread":0.3098642571532654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}