{"id":"W4404723672","doi":"10.1186/s41181-024-00313-8","title":"SPECT/CT imaging of EGFR-positive head and neck squamous cell carcinoma patient-derived xenografts with 203Pb-PSC-panitumumab in NRG mice","year":2024,"lang":"en","type":"article","venue":"EJNMMI Radiopharmacy and Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Northern Alberta Institute of Technology; Princess Margaret Cancer Centre; University of Toronto; University of Alberta","funders":"","keywords":"Panitumumab; Head and neck; Head and neck squamous-cell carcinoma; Basal cell; Medicine; Head and neck cancer; Nuclear medicine; Cancer research; Internal medicine; Cetuximab; Colorectal cancer; Cancer; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004459688,0.0006104503,0.0006103776,0.0005441759,0.0001548849,0.0002764769,0.0003476153,0.0006361394,0.001312131],"category_scores_gemma":[0.0001044008,0.000393548,0.000426701,0.0004079128,0.0002516422,0.0003299853,0.0001613698,0.0009123981,0.0005256608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000466932,"about_ca_system_score_gemma":0.0004216913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002842692,"about_ca_topic_score_gemma":0.003538883,"domain_scores_codex":[0.9998587,0.00002930518,0.000007955023,0.00003617168,0.00003662715,0.00003113529],"domain_scores_gemma":[0.999933,0.000009265561,0.00001511785,0.000008943372,0.00001569214,0.00001790218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003724639,0.00007307885,0.0002592415,0.00006552444,0.00001367896,0.0001451075,0.00001995532,0.0002799866,0.9971241,0.00005947277,0.000149348,0.00143805],"study_design_scores_gemma":[0.0001732075,0.003072987,0.007143761,0.0000290054,0.0001546483,0.002027733,0.00007649109,0.007573847,0.9744588,0.0000712054,0.005196642,0.00002173067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766449,0.005497717,0.009728673,0.0003051518,0.00008612088,0.0002536187,0.002167524,0.0005015888,0.004814667],"genre_scores_gemma":[0.9621366,0.006044078,0.01702106,0.0002397546,0.00002670365,0.0003927658,0.003655081,0.0001389836,0.01034497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002842692,"threshold_uncertainty_score":0.005652249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00872783416488636,"score_gpt":0.265972468446007,"score_spread":0.2572446342811207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}