{"id":"W4404756460","doi":"10.1016/j.chom.2024.11.003","title":"Protection against Clostridioides difficile disease by a naturally avirulent strain","year":2024,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; University of Chicago","keywords":"Biology; Clostridioides; Strain (injury); Microbiology; Disease; Virology; Internal medicine; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002584819,0.0004558697,0.0004102988,0.0002926465,0.000210963,0.0002618537,0.0002388616,0.0002252755,0.0004830622],"category_scores_gemma":[0.0001062255,0.0003978258,0.0003898987,0.0006710301,0.0001699208,0.0001414297,0.0001582301,0.001040818,0.0009778466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005539366,"about_ca_system_score_gemma":0.0006126112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007431297,"about_ca_topic_score_gemma":0.000008234144,"domain_scores_codex":[0.9970923,0.00008297475,0.0004955214,0.0008950242,0.000623022,0.0008111226],"domain_scores_gemma":[0.9984878,0.00007866057,0.0000628936,0.0005832509,0.0001591109,0.0006283298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003521956,0.0005129559,0.00003733812,0.0009303487,0.00007499717,0.0005051888,0.0001322533,0.000005367191,0.9266561,0.00002296462,0.05318671,0.01758356],"study_design_scores_gemma":[0.001042672,0.0003280754,0.0002968012,0.0005410999,0.0001493849,0.00004370968,0.0001559534,0.0007561415,0.7965046,0.00001236045,0.199747,0.0004222115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96816,0.0218537,0.0001213699,0.003476119,0.0005087686,0.001555281,0.0009171274,0.0004594491,0.002948214],"genre_scores_gemma":[0.9807124,0.001609411,0.00006426786,0.0004078513,0.0005614747,0.0001338964,0.0007420423,0.0001186935,0.01565003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1465602,"threshold_uncertainty_score":0.9998474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441392981421698,"score_gpt":0.2644407115092787,"score_spread":0.2500267816950618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}