{"id":"W4404762391","doi":"10.1016/j.biopsych.2024.10.014","title":"Along Came the DSM—Melancholic Depression, the Dexamethasone Suppression Test, and How Psychiatry Lost the Brain","year":2024,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Treatment of Major Depression","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Dexamethasone suppression test; Melancholic depression; Depression (economics); Psychiatry; Psychology; Test (biology); Melancholia; Clinical psychology; Dexamethasone; Medicine; Psychoanalysis; Internal medicine; Biology; Mood","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.003134653,0.0003451441,0.0005765895,0.0008864669,0.000952837,0.003430548,0.0005781273,0.002501519,0.00187896],"category_scores_gemma":[0.009177376,0.0002148494,0.0003934735,0.0005476479,0.004447689,0.003969737,0.001293474,0.007041239,0.0004362017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0028948,"about_ca_system_score_gemma":0.003602891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007431109,"about_ca_topic_score_gemma":0.02283509,"domain_scores_codex":[0.998646,0.0007114577,0.0001175649,0.00009023389,0.0003460035,0.00008882189],"domain_scores_gemma":[0.9958581,0.002462501,0.000305948,0.0002327509,0.0007513106,0.0003893732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000651164,0.0003662529,0.01497761,0.0006429562,0.0002553482,0.001168886,0.0009924407,0.0003700464,0.00210902,0.1684352,0.09080063,0.7192304],"study_design_scores_gemma":[0.0004008905,0.0008257213,0.02282263,0.002628393,0.0002632616,0.005831075,0.004447547,0.0009147025,0.001916331,0.2685758,0.6911762,0.0001972944],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.02218804,0.2300236,0.005764944,0.6917473,0.01834989,0.00004833371,0.0001774846,0.0001268845,0.03157351],"genre_scores_gemma":[0.4162384,0.2480639,0.01105407,0.2884696,0.01952983,0.000100753,0.0001579261,0.0001106977,0.01627484],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9990472,"threshold_uncertainty_score":0.02100337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02295578491949935,"score_gpt":0.2896965923879188,"score_spread":0.2667408074684194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}