{"id":"W4404806732","doi":"10.3324/haematol.2024.285874","title":"Intracranial hemorrhage before start of prophylaxis in children with hemophilia: incidence, timing, and potential for prevention","year":2024,"lang":"en","type":"article","venue":"Haematologica","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Novo Nordisk; Sanofi; Swedish Orphan Biovitrum; CSL Behring; Bayer; Pfizer","keywords":"Medicine; Incidence (geometry); Pediatrics; Cumulative incidence; Population; Intracranial haemorrhage; Surgery; Complication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001886584,0.0001352549,0.0003503052,0.0001838293,0.00004697577,0.00002022696,0.00005616225,0.0001305775,0.00006927838],"category_scores_gemma":[0.00005050045,0.00008107587,0.00006880031,0.0002316069,0.0001526354,0.00008174601,0.00004102346,0.0001724788,0.000006182915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002974887,"about_ca_system_score_gemma":0.00008807606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001888134,"about_ca_topic_score_gemma":0.00002841713,"domain_scores_codex":[0.998971,0.00002953906,0.0002361892,0.0003062122,0.0002231973,0.0002337933],"domain_scores_gemma":[0.9996634,0.00003269635,0.0000370975,0.0001382439,0.00005629159,0.00007229031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003452416,0.00161071,0.7544991,0.005400409,0.0006237429,0.004779787,0.001158914,0.00001246387,0.005036307,0.002397645,0.0002612125,0.2207673],"study_design_scores_gemma":[0.01299208,0.03216309,0.8736274,0.00291944,0.000897758,0.02191714,0.0005030006,0.01645683,0.02416424,0.01339927,0.0001811665,0.0007785996],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967906,0.0005431657,0.0003143334,0.0006414083,0.00003137306,0.001482651,0.00001559085,0.00004839272,0.0001324195],"genre_scores_gemma":[0.9941307,0.00003691851,0.005065456,0.00001046457,0.00006033179,0.0001024207,0.00005021477,0.00001560307,0.0005279264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2199887,"threshold_uncertainty_score":0.3306178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01863391552993435,"score_gpt":0.2965615859941216,"score_spread":0.2779276704641873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}