{"id":"W4404829280","doi":"10.3390/v16121844","title":"miR-24-3p Is Antiviral Against SARS-CoV-2 by Downregulating Critical Host Entry Factors","year":2024,"lang":"en","type":"article","venue":"Viruses","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Viral entry; Furin; Biology; Coronavirus; Mechanism (biology); Effector; microRNA; Viral replication; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virus; Computational biology; Virology; Coronavirus disease 2019 (COVID-19); Gene; Immunology; Medicine; Genetics; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000177894,0.0005201423,0.0004601412,0.0003012553,0.00030724,0.0004446651,0.0002061047,0.0003122825,0.00137579],"category_scores_gemma":[0.000187233,0.0001494132,0.0004859016,0.00017126,0.0002711968,0.000208777,0.0002071891,0.0006300378,0.0006812211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003150754,"about_ca_system_score_gemma":0.0004811844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002892174,"about_ca_topic_score_gemma":0.0004856196,"domain_scores_codex":[0.9998189,0.00002695434,0.00001724088,0.00004234807,0.00006824084,0.0000263052],"domain_scores_gemma":[0.9999357,0.000009897852,0.00002305102,0.000007588273,0.00001147753,0.00001226313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001803999,0.00003531862,0.0002338372,0.0001364927,0.00001649659,0.0001098962,0.00001397956,0.0002410079,0.9919476,0.0003094556,0.0002017535,0.006573705],"study_design_scores_gemma":[0.00003558527,0.0003758297,0.002752763,0.00001288616,0.00004371623,0.000564568,0.00002525352,0.00146833,0.97218,0.0003066368,0.02222064,0.00001373262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9043946,0.03491231,0.03892494,0.001124054,0.0005832178,0.0002950194,0.002304696,0.001596604,0.01586442],"genre_scores_gemma":[0.9637513,0.008487917,0.0204658,0.0003258592,0.00008429162,0.0001379849,0.001503054,0.000104955,0.005138725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137579,"threshold_uncertainty_score":0.004602492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07577240400773386,"score_gpt":0.3940609987098295,"score_spread":0.3182885947020956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}