{"id":"W4404885849","doi":"10.1136/bmjopen-2024-085025","title":"Protocol for a multicentre randomised triple-blind controlled trial assessing the clinical efficacy of intra-articular platelet-rich plasma injections versus placebo in symptomatic knee osteoarthritis (PIKOA)","year":2024,"lang":"en","type":"article","venue":"BMJ Open","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Placebo; Osteoarthritis; Clinical trial; Visual analogue scale; Randomized controlled trial; Platelet-rich plasma; Physical therapy; Adverse effect; Internal medicine; Platelet; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0307254,0.008130517,0.0136371,0.002368356,0.004736785,0.004250234,0.003951171,0.01067626,0.104566],"category_scores_gemma":[0.03198886,0.003374676,0.00455811,0.003479928,0.00544345,0.003931788,0.001907223,0.0115784,0.02168966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004011766,"about_ca_system_score_gemma":0.01474314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001868599,"about_ca_topic_score_gemma":0.004425658,"domain_scores_codex":[0.9714996,0.01681087,0.002501798,0.003346824,0.003257177,0.0025838],"domain_scores_gemma":[0.9801154,0.005745356,0.003828747,0.00285954,0.004274281,0.003176684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9372203,0.009163725,0.0004679156,0.01298648,0.001270558,0.0002317586,0.0003094571,0.000978307,0.001732295,0.003694495,0.01626081,0.01568392],"study_design_scores_gemma":[0.9581304,0.01721499,0.0008821803,0.001456823,0.0004239783,0.00004838372,0.00005188519,0.0009870467,0.0004324865,0.001391327,0.01890637,0.00007414872],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001563444,0.0002907421,0.00105236,0.0001908023,0.0007574153,0.9940042,0.0009509048,0.0001311255,0.001058906],"genre_scores_gemma":[0.002310926,0.0001173664,0.00142097,0.0003014611,0.0001089762,0.9950061,0.0001705951,0.000007092534,0.0005565402],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.104566,"threshold_uncertainty_score":0.3498082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1379415867332257,"score_gpt":0.4955233742043956,"score_spread":0.3575817874711699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}