{"id":"W4404948696","doi":"10.1016/j.esmogo.2024.100111","title":"This is not Lynch syndrome: lessons from misattributed diagnoses in constitutional mismatch repair deficiency","year":2024,"lang":"en","type":"article","venue":"ESMO Gastrointestinal Oncology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University; McGill University Health Centre","funders":"","keywords":"Lynch syndrome; Medicine; DNA mismatch repair; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009331852,0.00039592,0.0005146021,0.001960921,0.001322141,0.002292373,0.001131919,0.001999382,0.001165503],"category_scores_gemma":[0.0635196,0.0003482062,0.0003048661,0.001205304,0.00297883,0.00489658,0.002145846,0.003368198,0.0004612373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00147713,"about_ca_system_score_gemma":0.001589192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006188885,"about_ca_topic_score_gemma":0.007599142,"domain_scores_codex":[0.9949486,0.002501535,0.0006106498,0.0005775903,0.001023511,0.0003380641],"domain_scores_gemma":[0.9674237,0.0204479,0.005110834,0.002085829,0.003467996,0.001463885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0003131011,0.00009638345,0.5352467,0.0008308174,0.0001563885,0.08633374,0.01684617,0.001130113,0.001071665,0.01745261,0.04970063,0.2908216],"study_design_scores_gemma":[0.00008626143,0.000515585,0.2249539,0.006787784,0.0002159625,0.4584323,0.06138607,0.005980793,0.002117059,0.09728463,0.1418906,0.0003490017],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4751916,0.0972683,0.03688522,0.3557295,0.008579304,0.0001751835,0.0007255158,0.0004320201,0.02501344],"genre_scores_gemma":[0.9491816,0.02376745,0.009584935,0.01266274,0.003616535,0.00002438897,0.0001298755,0.00008430504,0.0009480854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009331852,"threshold_uncertainty_score":0.04935217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04332672606377994,"score_gpt":0.3450683556783465,"score_spread":0.3017416296145665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}