{"id":"W4404976932","doi":"10.1002/adfm.202420254","title":"An Engineered Recombinant Spider Silk Protein Providing Disulfide‐Locked Control over Self‐Assembly and Fiber Formation","year":2024,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"Silk-based biomaterials and applications","field":"Materials Science","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Ministère de la Défense Nationale; Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; Compute Canada; Canadian Institutes of Health Research; Mitacs; University of Toronto; Dalhousie University; Cancer Research Institute; McGill University; Dalhousie Medical Research Foundation; Beatrice Hunter Cancer Research Institute","keywords":"Materials science; Spider silk; SILK; Disulfide bond; Recombinant DNA; Self-assembly; Fiber; Nanotechnology; Composite material; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005573591,0.0002959629,0.0003274049,0.0001097936,0.0002588554,0.0006149847,0.0001298911,0.0001217386,0.001589355],"category_scores_gemma":[0.00005404585,0.0002429763,0.00004889792,0.0001604747,0.00005085333,0.001449908,0.00004031132,0.00005372792,0.0003122299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001081952,"about_ca_system_score_gemma":0.00006576291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003117788,"about_ca_topic_score_gemma":0.000003321176,"domain_scores_codex":[0.9980698,0.0001186863,0.0005791162,0.000572964,0.000283716,0.0003756898],"domain_scores_gemma":[0.9992017,0.000115694,0.0001471611,0.0003022858,0.0001000689,0.0001330626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001909421,0.0000951677,0.000003226682,0.0002137303,0.00001621842,0.000005742918,0.00005349481,0.0001411244,0.9934621,0.004724063,0.0003816993,0.0007124752],"study_design_scores_gemma":[0.0008941428,0.000205879,0.0007081461,0.0001687232,0.00004597925,0.00003780991,0.00002987847,0.0007275245,0.9888613,0.002121148,0.005859664,0.0003397618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917039,0.0001539397,0.004014852,0.0003870322,0.001515077,0.001188301,0.0003520566,0.0006282681,0.00005656877],"genre_scores_gemma":[0.9945714,0.0000158183,0.003352044,0.0001201891,0.0004247485,0.001009346,0.0001638648,0.00005149471,0.0002911247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005477965,"threshold_uncertainty_score":0.9993233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00921261305846673,"score_gpt":0.2403551708913195,"score_spread":0.2311425578328528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}