{"id":"W4404997121","doi":"10.1007/s40273-024-01456-x","title":"Cost-Effectiveness of Capivasertib as a Second-Line Therapy for Advanced Breast Cancer","year":2024,"lang":"en","type":"article","venue":"PharmacoEconomics","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Fulvestrant; Medicine; Cost effectiveness; Anastrozole; Breast cancer; Quality of Life Research; Oncology; Health economics; Internal medicine; Cancer; Gynecology; Tamoxifen; Public health; Nursing; Risk analysis (engineering)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002619434,0.000256309,0.0005079043,0.0001297265,0.00004234091,0.00001938607,0.0001250011,0.00006343321,0.001454396],"category_scores_gemma":[0.00000845968,0.0002360281,0.0002222804,0.0001253464,0.00009385445,0.0002735235,0.00002444127,0.0001753927,0.00002903097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000377096,"about_ca_system_score_gemma":0.0004270561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004342953,"about_ca_topic_score_gemma":0.00000956667,"domain_scores_codex":[0.9987959,0.00003496393,0.0003418322,0.0004311004,0.00007735636,0.000318818],"domain_scores_gemma":[0.9990498,0.0003275001,0.00009776441,0.0002299919,0.0001455722,0.0001493712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0146618,0.0001907699,0.0006261221,0.001601944,0.000968779,0.00001286779,0.0003317553,0.00152953,0.4998787,0.0007557258,0.0001700568,0.4792719],"study_design_scores_gemma":[0.01150623,0.0003974281,0.002417282,0.0005323794,0.0001877629,0.0002039696,0.0001021393,0.003906792,0.8341352,0.001650181,0.1445792,0.0003813562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768801,0.01406957,0.002219352,0.001367644,0.001176895,0.002508842,0.001314609,0.0001649755,0.0002980263],"genre_scores_gemma":[0.9937248,0.001989702,0.0006161736,0.001227971,0.00048323,0.001319785,0.00006494873,0.0001102571,0.0004630891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4788906,"threshold_uncertainty_score":0.9994584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04592795873233327,"score_gpt":0.4144842457790218,"score_spread":0.3685562870466885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}