{"id":"W4405014532","doi":"10.1039/d4cc05367b","title":"TPDYs: strained macrocyclic diynes for bioconjugation processes","year":2024,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Université de Montréal; Centre in Green Chemistry and Catalysis","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Bioconjugation; Chemistry; Nanotechnology; Combinatorial chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001776823,0.0001832318,0.0001798377,0.00003204417,0.0001452544,0.0001172757,0.001014902,0.0001785394,0.00041627],"category_scores_gemma":[0.001784548,0.0001831022,0.0001095809,0.0003094401,0.0002552184,0.00009542828,0.0002409598,0.0002638419,0.00003623924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001116855,"about_ca_system_score_gemma":0.0001645282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004507051,"about_ca_topic_score_gemma":0.000002059415,"domain_scores_codex":[0.998939,0.00001635537,0.0003423171,0.0003348032,0.0001307167,0.0002367494],"domain_scores_gemma":[0.9962323,0.002097101,0.00006079827,0.001378843,0.0001341961,0.00009671161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007375555,0.00007787618,0.00001282296,0.0009863067,0.00004772945,3.447228e-7,0.0002422225,1.385931e-7,0.980012,0.002038427,0.0009808713,0.01559386],"study_design_scores_gemma":[0.0001752291,0.00000315127,0.000001662949,0.0002085225,0.00006774936,0.00001570541,0.0002230091,0.0008311276,0.9061963,0.008217579,0.08386156,0.0001984326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5639023,0.04644454,0.05513348,0.05293553,0.0007827293,0.001941513,0.002217486,0.007854453,0.268788],"genre_scores_gemma":[0.9633717,0.0002220717,0.03386984,0.00004669612,0.0002151392,0.0004088769,0.0004852229,0.00005790375,0.001322529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3994694,"threshold_uncertainty_score":0.7466689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05661667227840549,"score_gpt":0.3575233798433112,"score_spread":0.3009067075649057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}