{"id":"W4405015583","doi":"10.1021/jacs.4c11054","title":"Intramolecular Csp<sup>3</sup>-H Activation at a Platinum(IV) Center Resulting from O<sub>2</sub> Activation: The Role of a Proton-Responsive Ligand and Trans Influence","year":2024,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brandon University; University of Calgary; University of British Columbia","funders":"University of British Columbia Graduate School; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund; Canada Foundation for Innovation","keywords":"Chemistry; Intramolecular force; Platinum; Ligand (biochemistry); Center (category theory); Proton; Stereochemistry; Medicinal chemistry; Crystallography; Catalysis; Organic chemistry; Nuclear physics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003926601,0.0001837966,0.0003031101,0.00002281721,0.0001319503,0.00006689796,0.0002862979,0.00009732818,0.00003024973],"category_scores_gemma":[0.0009118261,0.0001198314,0.0003642207,0.0004430231,0.0004668037,0.0001842195,0.0001395159,0.0006021957,6.918645e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002920488,"about_ca_system_score_gemma":0.0001651177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000401622,"about_ca_topic_score_gemma":2.746289e-7,"domain_scores_codex":[0.9983743,0.00008431806,0.0005624779,0.0002394488,0.0005616479,0.0001777925],"domain_scores_gemma":[0.9975076,0.001244049,0.0006759281,0.0002606382,0.0002323627,0.00007945373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000363491,0.00004304746,0.001620951,0.00006334658,0.0002769598,8.716138e-7,0.004187772,0.0006021027,0.9885159,0.000009868611,0.0004275301,0.003888167],"study_design_scores_gemma":[0.000477084,0.00002099659,0.0006356561,0.0003763581,0.0000952132,0.00004673222,0.001692742,0.005361994,0.9877501,0.0005224338,0.002896925,0.000123728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957028,0.0001129782,0.001677226,0.002194465,0.00002278655,0.0001588028,0.0000477217,0.00001945333,0.00006378088],"genre_scores_gemma":[0.9977545,0.00005599333,0.001319404,0.0005111764,0.0002838165,0.00001656455,0.00001290862,0.0000277029,0.00001798036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004759891,"threshold_uncertainty_score":0.4886582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007923132149843628,"score_gpt":0.2526294566898526,"score_spread":0.244706324540009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}