{"id":"W4405031441","doi":"10.1016/j.inpsyc.2024.100012","title":"Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)","year":2024,"lang":"en","type":"article","venue":"International Psychogeriatrics","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"Genentech; National Institutes of Health; H. Lundbeck A/S; National Institute of Mental Health; Eisai; U.S. Department of Defense; Sunovion; National Institute on Aging; Eli Lilly and Company; ACADIA Pharmaceuticals; Biogen","keywords":"Apathy; Dementia; Methylphenidate; Cognition; Disease; Psychology; Alzheimer's disease; Psychiatry; Clinical psychology; Medicine; Internal medicine; Attention deficit hyperactivity disorder","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004431095,0.0007616869,0.002295771,0.0004141071,0.0003041284,0.0008723534,0.000576108,0.0006890601,0.001652268],"category_scores_gemma":[0.00408749,0.0004222818,0.001927497,0.0004982734,0.0003077659,0.0004478549,0.0004791869,0.001162424,0.0001383808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003483242,"about_ca_system_score_gemma":0.0004437837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006252087,"about_ca_topic_score_gemma":0.00171093,"domain_scores_codex":[0.998497,0.0008937588,0.0001431284,0.0001799874,0.0002242393,0.00006187887],"domain_scores_gemma":[0.997543,0.0008838519,0.0009077738,0.0001639837,0.0002247659,0.000276621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6613457,0.00243748,0.2680906,0.001764364,0.02152342,0.0001235442,0.0001094928,0.0007529706,0.002369106,0.0001046814,0.001365478,0.04001321],"study_design_scores_gemma":[0.1549287,0.04232916,0.7828367,0.0002185265,0.01384233,0.0003588914,0.00007755187,0.002437618,0.0008371257,0.0003550595,0.00170158,0.00007675794],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892573,0.007945797,0.0002230172,0.0001715431,0.00007265041,0.0004294585,0.001070259,0.00001568277,0.0008143187],"genre_scores_gemma":[0.9960103,0.001383768,0.0004441129,0.0001053055,0.000101286,0.0004108454,0.00115758,0.00000403028,0.0003827859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004431095,"threshold_uncertainty_score":0.02343416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03194292783595093,"score_gpt":0.3589286320694351,"score_spread":0.3269857042334842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}