{"id":"W4405038077","doi":"10.1182/blood-2024-200914","title":"Outcomes By Refractory Status and Prior Therapies Received in Patients with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL) from the ECHELON-3 Study","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Diffuse large B-cell lymphoma; Refractory (planetary science); Medicine; Internal medicine; Lymphoma; Oncology; Ibrutinib; Leukemia; Biology; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00122524,0.0004049476,0.0007973242,0.0003847666,0.0003248862,0.000798176,0.0004367491,0.0005014741,0.001196263],"category_scores_gemma":[0.001227515,0.0002055751,0.001885843,0.0007108296,0.0002875444,0.0005980061,0.0007029206,0.0007894931,0.0001886369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005173794,"about_ca_system_score_gemma":0.0004149019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001983918,"about_ca_topic_score_gemma":0.004976791,"domain_scores_codex":[0.9994063,0.0002137631,0.00007169431,0.0001377796,0.00006885641,0.000101597],"domain_scores_gemma":[0.9993951,0.000102718,0.0002073284,0.00006393432,0.00004779913,0.0001830932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.09650075,0.0007357567,0.8790469,0.0003936756,0.005890614,0.0003242137,0.0002699429,0.0008609775,0.001769802,0.0002026153,0.002686482,0.01131821],"study_design_scores_gemma":[0.01390703,0.009308308,0.9638001,0.0001504568,0.005779103,0.0005561821,0.0004556912,0.001264772,0.0005934904,0.0005157805,0.003621556,0.0000475747],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958678,0.00141108,0.00007696966,0.00009495624,0.0000205891,0.00008445558,0.001876283,0.000004177337,0.0005636473],"genre_scores_gemma":[0.9957873,0.000282939,0.00005937583,0.0001876999,0.0000425649,0.0001071313,0.003321372,0.000004001797,0.0002074876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001983918,"threshold_uncertainty_score":0.00647974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006753079207637134,"score_gpt":0.2281801692373907,"score_spread":0.2214270900297536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}