{"id":"W4405038340","doi":"10.1002/anie.202419996","title":"Self‐Assembly and Biological Properties of Highly Fluorinated Oligonucleotide Amphiphiles","year":2024,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"European Regional Development Fund; Fonds de recherche du Québec – Nature et technologies; Regione Lombardia; Natural Sciences and Engineering Research Council of Canada; European Commission; Ministero della Salute; Canada Foundation for Innovation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Nucleic acid; Oligonucleotide; Amphiphile; Nanocarriers; Molecular beacon; DNA; Small molecule; Combinatorial chemistry; Chemistry; Computational biology; Nanotechnology; Biophysics; Biology; Biochemistry; Materials science; Nanoparticle; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831153,0.0002053583,0.00006211515,0.0001512467,0.00009368191,0.0001648196,0.0000816185,0.0002327316,0.000279972],"category_scores_gemma":[0.0002557881,0.00009354293,0.000114211,0.00008109243,0.0001627906,0.000183049,0.0001106737,0.0001982367,0.0001132199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001905036,"about_ca_system_score_gemma":0.0001229709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000492937,"about_ca_topic_score_gemma":0.0003814291,"domain_scores_codex":[0.999918,0.00001416485,0.000005968228,0.00001928465,0.00002797147,0.00001459983],"domain_scores_gemma":[0.999864,0.00002967358,0.00004907205,0.000006472123,0.00003043956,0.0000203491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001663694,0.000005829809,0.00009034962,0.00001514383,0.00000145471,0.00001256791,0.0000123337,0.00007894787,0.998485,0.00007384008,0.00001123091,0.001196637],"study_design_scores_gemma":[0.000003316365,0.0001211189,0.002137016,0.000002392356,0.000004062063,0.00007640161,0.000006728708,0.001056743,0.9954422,0.00002455414,0.001120601,0.000004896929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917979,0.001922473,0.004997313,0.0000499708,0.00001245637,0.00002003818,0.0001001676,0.00002958182,0.001070068],"genre_scores_gemma":[0.9949477,0.0006563129,0.003169025,0.00002212352,0.000006136943,0.00001785517,0.0001181284,0.000007225227,0.00105554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000492937,"threshold_uncertainty_score":0.001382172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01518943972075012,"score_gpt":0.2581059480698202,"score_spread":0.2429165083490701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}