{"id":"W4405038770","doi":"10.1182/blood-2024-203456","title":"Additional Induction Intrathecal Cytarabine for Patients with CNS2 Disease at Diagnosis Is Not Beneficial for Patients with B-ALL Treated on Children's Oncology Group Protocols AALL0932 and AALL1131","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Cytarabine; Internal medicine; Oncology; Intrathecal; Group B; Chemotherapy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002055916,0.0001816594,0.0007530209,0.0001513645,0.0002304602,0.0008421094,0.0004899304,0.0003485539,0.002103007],"category_scores_gemma":[0.00635539,0.0001050448,0.001348616,0.0004433721,0.0002982805,0.0005176463,0.0003759373,0.001087563,0.0001789867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009812663,"about_ca_system_score_gemma":0.002487411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002621912,"about_ca_topic_score_gemma":0.008689468,"domain_scores_codex":[0.9987389,0.0006117251,0.0001141562,0.000204343,0.0001987552,0.0001321205],"domain_scores_gemma":[0.9971365,0.001110712,0.001099988,0.0001815602,0.0001154135,0.0003558347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1498929,0.001512244,0.5394251,0.002330004,0.007796367,0.0003833174,0.0003417032,0.006964799,0.005885523,0.001938955,0.01951674,0.2640124],"study_design_scores_gemma":[0.0237968,0.03937705,0.876884,0.0009789201,0.008092645,0.001114811,0.0002997443,0.008296945,0.003736162,0.003514126,0.03386058,0.00004830873],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856066,0.005757897,0.0006180041,0.001816323,0.000153453,0.0002321466,0.001604671,0.00005915181,0.004151867],"genre_scores_gemma":[0.9957494,0.001044035,0.0005402805,0.0007839673,0.00007459894,0.0001223617,0.001217687,0.00001414142,0.0004535511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002621912,"threshold_uncertainty_score":0.01087284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01405608732935281,"score_gpt":0.2783919837001649,"score_spread":0.2643358963708121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}