{"id":"W4405039028","doi":"10.1182/blood-2024-206247","title":"Final Results of the Canadian Myeloma Research Group Trial of Cybord Induction, Double-Alkylator Conditioning with High-Dose Intravenous Busulfan + Melphalan, ASCT and Continuous Lenalidomide Maintenance for Patients with Newly Diagnosed Multiple Myeloma (CMRG-001)","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Princess Margaret Cancer Centre; Vancouver General Hospital; BC Cancer Agency; Saint John Regional Hospital; Hôpital Maisonneuve-Rosemont; Concordia University; McGill University; University of Saskatchewan; Queen Elizabeth II Health Sciences Centre; Ottawa Hospital; University Health Network; Dalhousie University","funders":"","keywords":"Melphalan; Medicine; Busulfan; Lenalidomide; Multiple myeloma; Maintenance therapy; Plerixafor; Surgery; Oncology; Internal medicine; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002624895,0.001018743,0.001201935,0.0002277493,0.0006717998,0.001522527,0.001043743,0.001077355,0.004542811],"category_scores_gemma":[0.00208466,0.000338402,0.001323677,0.0005120749,0.0008897829,0.0004526145,0.0004567624,0.002006256,0.0007325127],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004636627,"about_ca_system_score_gemma":0.007981615,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.06241374,"about_ca_topic_score_gemma":0.1884314,"domain_scores_codex":[0.9991283,0.0002750989,0.00003543506,0.0001597009,0.0002146743,0.0001868403],"domain_scores_gemma":[0.998901,0.0001224941,0.0001818654,0.00008578505,0.0001480699,0.0005609001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8914334,0.003797406,0.01649579,0.0008069176,0.004158482,0.0001136199,0.0001667448,0.001163103,0.003589393,0.0006451873,0.02632375,0.05130629],"study_design_scores_gemma":[0.7329683,0.09622797,0.1296366,0.0002638688,0.006458608,0.0002336503,0.0001380775,0.001015622,0.001934588,0.000757882,0.03025384,0.0001108827],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9400546,0.01016927,0.000351238,0.003278557,0.0005933275,0.003886531,0.02197776,0.0001167086,0.01957191],"genre_scores_gemma":[0.9659996,0.001707979,0.00103227,0.002816645,0.0002319532,0.001134311,0.02118015,0.00003744788,0.005859661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9953634,"threshold_uncertainty_score":0.1241009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03033523071453066,"score_gpt":0.2867234803775743,"score_spread":0.2563882496630437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}