{"id":"W4405040029","doi":"10.1182/blood-2024-199996","title":"Presence of Leukemia-Related Basophils and Mast Cells with Atypical Immunophenotype during Induction Should Not be Interpreted As Measurable Residual Disease in Children with Acute Myeloid Leukemia with <i>RUNX1</i>::<i>RUNX1T1</i>","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Terry Fox Research Institute; University of British Columbia; University Health Network","funders":"","keywords":"Immunophenotyping; Myeloid leukemia; RUNX1; Leukemia; Immunology; Medicine; Preleukemia; Biology; Haematopoiesis; Flow cytometry; Genetics; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005805898,0.0002020593,0.0003173124,0.0006002709,0.0002425617,0.0004213537,0.0002535801,0.0002238541,0.0006798079],"category_scores_gemma":[0.0008024682,0.0001292318,0.0002021107,0.0005587254,0.0003929306,0.0002961953,0.0003457023,0.0002118296,0.0001986066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002781752,"about_ca_system_score_gemma":0.0002635075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00235123,"about_ca_topic_score_gemma":0.003349045,"domain_scores_codex":[0.9995373,0.00008650661,0.0000790414,0.0001031092,0.000102483,0.00009161726],"domain_scores_gemma":[0.9995086,0.0001021034,0.0002510848,0.00003529957,0.00004891367,0.0000539784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007304799,0.000008626183,0.9929669,0.00002294046,0.000007120149,0.001040023,0.0001984244,0.00003595587,0.002501561,0.00001301391,0.00004793446,0.003084448],"study_design_scores_gemma":[0.000003254892,0.0001245236,0.9922196,0.00001079769,0.00001811913,0.004631977,0.0005346673,0.00006845775,0.00176092,0.00001755883,0.0006070848,0.000003088142],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989651,0.0003257192,0.0001775553,0.000009724919,0.000002654667,0.00001528224,0.0002441551,0.000004665525,0.000255154],"genre_scores_gemma":[0.9989496,0.0001809333,0.0003728217,0.00001671502,0.000005338994,0.00001693969,0.0003550961,0.000003288678,0.00009916917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00235123,"threshold_uncertainty_score":0.00467509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009527451395144439,"score_gpt":0.2274879366083889,"score_spread":0.2179604852132444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}