{"id":"W4405040628","doi":"10.1055/s-0044-1800833","title":"Precision Medicine in Rare Bleeding Disorders","year":2024,"lang":"en","type":"review","venue":"Seminars in Thrombosis and Hemostasis","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Lawrence College; Queen's University","funders":"","keywords":"Medicine; Incidence (geometry); Coagulation Disorder; Pediatrics; Coagulation; Coagulopathy; Major bleeding; Factor IX; Population; Internal medicine; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00203846,0.001415158,0.003524761,0.005114865,0.0003062513,0.001935158,0.0009467342,0.001987859,0.00782049],"category_scores_gemma":[0.003647546,0.0004531103,0.00117326,0.003214517,0.0008280275,0.001953184,0.001463745,0.00255931,0.002088338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009965858,"about_ca_system_score_gemma":0.001952368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009149043,"about_ca_topic_score_gemma":0.001966994,"domain_scores_codex":[0.9993623,0.0001729685,0.0001229046,0.00007786269,0.0002123942,0.00005149655],"domain_scores_gemma":[0.9973963,0.001779516,0.0003890051,0.00006474787,0.0002662794,0.0001040062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001206865,0.00004452843,0.0001122077,0.04183825,0.0004275237,0.0001890226,0.00004906258,0.0003794495,0.0006737554,0.003478522,0.04343304,0.9092539],"study_design_scores_gemma":[0.0001856872,0.0002162547,0.0009325366,0.02701133,0.001194472,0.00155542,0.00004845585,0.0002391494,0.0003928558,0.004689712,0.9634889,0.00004524782],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002602866,0.9989566,0.00009900468,0.0002344247,0.0002807805,0.000003608289,0.00001190401,0.000007192828,0.0003805286],"genre_scores_gemma":[0.0004684145,0.99775,0.0002165224,0.0005702766,0.0006365252,0.000007075574,0.00002406933,0.000001656301,0.0003255011],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00782049,"threshold_uncertainty_score":0.02616215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1020027120090377,"score_gpt":0.4303528661103495,"score_spread":0.3283501541013117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}