{"id":"W4405040632","doi":"10.1182/blood-2024-211167","title":"Real World Evidence of Outcomes of Patients Treated with Talquetamab in a Heavily Pretreated Population with Multiple Myeloma with High Exposure to Prior BCMA Therapies- a Report from the IMWG Consortium","year":2024,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Multiple myeloma; Pomalidomide; Population; Internal medicine; Carfilzomib; Oncology; Lenalidomide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002572862,0.0001128067,0.0002578099,0.0009612624,0.0002755222,0.001197296,0.0003475368,0.0003118692,0.001394759],"category_scores_gemma":[0.007421446,0.00009231763,0.000251051,0.001598995,0.0004172106,0.0005325587,0.00060716,0.0003913532,0.0001495983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006595923,"about_ca_system_score_gemma":0.0004813711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00165649,"about_ca_topic_score_gemma":0.001809324,"domain_scores_codex":[0.9983143,0.0007209033,0.0002070524,0.0001792455,0.0004314155,0.000147122],"domain_scores_gemma":[0.9863394,0.00307965,0.008530106,0.000440831,0.0009072089,0.000702626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007137751,0.00004383203,0.9928778,0.00004071218,0.0001082603,0.00008342986,0.00008443899,0.00009745301,0.0001359801,0.00004440762,0.0003891737,0.005380814],"study_design_scores_gemma":[0.00006643835,0.0003325201,0.9974607,0.00004280612,0.0001114959,0.0003883126,0.0002337789,0.0001845658,0.0001785614,0.0000676484,0.0009248861,0.000008297997],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944952,0.001871121,0.00008522444,0.0005990996,0.000007337314,0.00001575485,0.001183789,0.000004433899,0.001737989],"genre_scores_gemma":[0.9988054,0.0002887321,0.00003484306,0.00008601556,0.00001648525,0.000008434072,0.0007167133,0.000001650608,0.00004173391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002572862,"threshold_uncertainty_score":0.01360679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990528795307521,"score_gpt":0.2882926644433249,"score_spread":0.2683873764902497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}